Design of a Pharmacokinetics Study with Multiple Doses of Accordion Pill™ Carbidopa/Levodopa in Patients with Parkinson’s disease
Objective: To perform a pharmacokinetic (PK) study of the Accordion Pill™ carbidopa/levodopa (AP-CD/LD) and to determine if multiple doses can provide continuous delivery of LD.…A phase Ib trial studying the safety and tolerability of IRL790 in patients with Parkinson’s disease and levodopa-induced dyskinesia
Objective: The primary objective was to investigate the safety and tolerability of IRL790 in PD patients with LID in a randomized controlled trial. Background: IRL790…Comparative results between preoperative acute levodopa challenge test and deep brain stimulation
Objective: Our aim is to compare motor clinical benefits after acute levodopa challenge test, with those obtained further with deep brain stimulation (DBS). Background: DBS…Identification of L-DOPA “on/off” states using speech-based analysis in Parkinson’s disease subjects
Objective: The aim of this study is to assess the use of semantic, prosodic, and acoustic speech features to better characterize PD signs with respect…Central Aortic Pressure in Parkinson’s Disease and Levodopa Effect
Objective: Central aortic pressure (CAP) is the systolic blood pressure at the root of the aorta. In young people CAP is lower than the peripheral…Managing severe dyskinesia in Parkinson’s Disease using 24-hour Levodopa/Carbidopa Intestinal Gel Infusion
Objective: We report the effective treatment of troublesome dyskinesias in Parkinson’s disease (PD), unresponsive to 16-hour daytime infusions, using 24-hour Levodopa/Carbidopa Intestinal Gel (LCIG). Background:…Effect of levodopa-carbidopa intestinal gel on dyskinesia: Design of an open-label, randomized multicenter 12-week study in advanced Parkinson’s disease patients
Objective: To examine the effect of levodopa-carbidopa intestinal gel (LCIG, designated carbidopa-levodopa enteral suspension in the US) treatment relative to that of optimized medical treatment…Sleep quality in patients with advanced Parkinson’s disease treated with levodopa/carbidopa intestinal gel infusion
Objective: To describe the effects of levodopa/carbidopa intestinal gel (LCIG) infusion on sleep quality in patients with advanced Parkinson's disease (PD). Background: Worsening of sleep…How Usual Is Skin Rashes During Treatment With Levodopa / Benserazide Hydrochloride?
Objective: To clarify the possible associations of levodopa / benserazidehydrochloride usage and skin rashes. Background: Levodopa/benserazide hydrochloride is one of the best dopaminergic drug used…Wearing Off Frequency in Different Hoehn-Yahr Stages in Parkinson’s Disease
Objective: To determine wearing off frequency in different stages of Parkinson’s disease (PD). Background: Levodopa is the gold standard in the symptomatic treatment of PD. The…
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