Clinical profile of early-onset Parkinson’s disease
Objective: Describe motor and non-motor symptoms, complications and treatment in patients with early-onset Parkinson's disease (EOPD) Background: PD usually affecting people over age 60, clinically…Association between Fecal Bile Acids and Levodopa Response in Patients with Parkinson’s Disease
Objective: We sought to determine whether fecal bile acids (BAs) could affect levodopa response assessed by levodopa challenge test (LCT) in patients with Parkinson’s disease…Levodopa response is an inadequate and often biased correlate of STN-DBS outcomes
Objective: To investigate the reliability of the relationship between levodopa response and subthalamic nucleus (STN) DBS outcomes in Parkinson disease (PD). Background: Levodopa response (LR)…The bypassing and embedded PEG J
Objective: Our aim is to highlight the improvement on quality of life of using a duodenal levodopa infusion. In addition, we want to emphasize the continuing…If Oral Levodopa is not Possible, Keep Calm and Breathe Deeply
Objective: Include inhaled levodopa as a therapeutic option in those patients who, due to post-surgical problems, cannot use oral treatments. Background: The development of motor…Wearable sensors and AI in Parkinson’s disease – How continuous symptom and treatment response monitoring can enable better clinical decision making – Interim results from an observational study
Objective: To investigate how continuous objective information on motor symptoms and treatment response combined with subjective patient reported insights can be used to optimize Parkinson’s…Nocturnal Use of Add-On Medications for Parkinson’s Disease: Post Hoc Analysis of the COSMOS Study
Objective: To assess nighttime use of add-on medications for Parkinson’s disease (PD) in a post hoc analysis of the COSMOS (COmedication Study assessing Mono- and…Pre-treatment with Methanolic Extract Mucuna pruriens Seeds Attenuates Serotonin Gene Depletion, Motor Dysfunction and Anxiogenic Responses in a Rat Model of Parkinsonism
Objective: Investigate neuroprotective and genoprotective effects of methanolic Mucuna pruriens (Mp) seed extract in a paraquat-induced Parkinsonism rat model. Background: Paraquat exposure has been linked…Digital health technology (DHT) derived features as sensitive measures of disease progression in early Parkinson’s disease under stable dopaminergic treatment
Objective: To evaluate the ability of DHT derived features from remotely collected active tests to measure disease progression in individuals with early Parkinson’s disease (PD)…Effect of Istradefylline on Motor and Non-motor Symptoms in Patients with Parkinson’s Disease: the ISTRA ADJUST PD Randomized, Controlled Study
Objective: To examine the effects of istradefylline on motor and non-motor symptoms in Parkinson’s disease (PD) patients with wearing-off phenomena. Background: Previous results [1,2] of…
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