MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Lewy bodies"

  • 2017 International Congress

    Impaired Color Vision in Patients with DLB or Prodromal DLB.

    B. Tousi, P. Flanigan, M. Khosravi (Cleveland, OH, USA)

    Objective: We sought to characterize the prevalence of color vision impairment in DLB patients and investigate how color vision impairment in DLB patients was associated with other…
  • 2017 International Congress

    Association of arterial stiffness with cognition in patients with Lewy body disorder

    J.Y. LEE, D.-W. Ryu, J.-S. Kim (Seoul, Republic of Korea)

    Objective: We aimed to investigate the association between arterial stiffness and cognitive function in patients with Lewy body disorder (LBD), including Parkinson disease (PD) and…
  • 2017 International Congress

    Striatal dopamine transporter abnormalities in pure autonomic failure and speculation about the relationship with Lewy bodies

    M. Yogo, M. Morita, M. Suzuki (Tokyo, Japan)

    Objective: To reveal dopamine transporter (DAT) abnormalities in pure autonomic failure (PAF) and speculate about the relationship with the Lewy body progression pathway.    Background:…
  • 2017 International Congress

    Characterization of Noncoding Variant(s) Driving Genome-Wide Association of the PARK10 Locus in Autopsy-Proven Parkinson Disease and Controls.

    J. Vance, K. Nuytemans, D. Gveric, L. Gomez, G. Beecham, E. Martin, W. Scott (Miami, FL, USA)

    Objective: Confirm the PARK10 locus as a major GWAS locus in autopsy-confirmed (AC) PD and AC controls and identify potential noncoding variants driving the association. …
  • 2017 International Congress

    Marked occipital hypometabolism on FDG-PET in patients with idiopathic RBD may predict Parkinson’s disease

    K. Kashihara, M. Kitayama, T. Hamaguchi (Okayama, Japan)

    Objective: In the present study, we tried to elucidate if the occipital hypometabolism detected by [(18) F]-fluoro-d-glucose (FDG) positron emission tomography (PET) scan in patients with idiopathic…
  • 2016 International Congress

    Protein levels of SV2A and VGLUT1 in brain tissue from patients with Parkinson’s disease, dementia with Lewy bodies and Alzheimer’s disease

    S. Frykman, M. Oosterhof, M.S. Ahmed, D. Howlet, T. Hortobagyi, P. Francis, D. Årsland (Huddinge, Sweden)

    Objective: The objective of this study was to investigate whether SV2A and/or VGLUT1 are suitable as markers for synaptic degeneration in neurodegenerative disorders and could…
  • 2016 International Congress

    Novel PET Tracers of alpha-synuclein for the diagnosis of Parkinson’s disease

    E. Tsika, A. Davranche, J. Molette, E. Gabellieri, S. Papin, S. Nampally, H. Kroth, D. Lowe, A. Pfeifer, A. Muhs (Lausanne, Switzerland)

    Objective: The aim of our project is to develop small molecular weight compounds (Morphomers™) which bind selectively to alpha-synuclein (aSyn) aggregates, in order to generate…
  • 2016 International Congress

    Targeted over-expression with AAV-mediated human α-synuclein in a rat model of Parkinson’s disease – Validation of novel fine motor functional effects

    R. Pussinen, T. Ahtoniemi, T. Huhtala, O. Kontkanen, A. Nurmi (Kuopio, Finland)

    Objective: Targeted over-expression of human α-synuclein using viral-vector mediated gene delivery into the substantia nigra of rats and non-human primates has been reported to lead…
  • 2016 International Congress

    Correlation between neuro-behavioral symptoms, cognition and gait in patients with dementia with Lewy bodies (DLB)

    B. Tousi, L. Mourany (Cleveland, OH, USA)

    Objective: To determine the prevalence of neurobehavioral disturbances and their relationship to gait and cognitive impairment in DLB. Background: The recent literature has conceptualized that…
  • 2016 International Congress

    The clinical characteristics of Lewy body disease showed autonomic failures preceding motor signs

    A. Miyake, T. Yamamoto, K. Ikeda, T. Furuya, M. Takashi, Y. Ito, Y. Nakazato, N. Tamura, N. Araki (Irumagun Moroyama Town, Japan)

    Objective: There are few cases of Lewy body disease who have been initially diagnosed as pure autonomic failure(PAF), because they had only autonomic symptoms for…
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