A Curious Case of Copper de-Compensation
Objective: To describe the investigation and management of a patient with Wilson’s disease who experienced late-onset neurological deterioration despite continued treatment. Background: Wilson’s disease is…Habenular Structural Connectivity Changes in Parkinson’s Disease: A 7T MRI Study
Objective: To assess if the structural connectivity of habenula (Hb) differs between Parkinson’s disease (PD) patients and healthy controls (HCs). Background: PD is marked by…MRI Visible Perivascular Spaces are Associated with Disease Duration and Severity in Parkinson’s Disease
Objective: Determine whether enlarged perivascular spaces (ePVS) in Parkinson's disease (PD) is associated with worsening motor symptoms and disease progression. Background: PVS are fluid-filled channels…DystoniaDBSNet: A novel deep learning biomarker of predictive treatment outcomes in dystonia
Objective: To develop an objective predictive measure of deep brain stimulation (DBS) treatment outcomes in dystonia. Background: Dystonia causes involuntary muscle contractions, affecting movements and…PSP: a Clinical Case
Objective: PSP is traditionally considered a neurodegenerative disease of late life. Its diagnostic criteria include the item “age of onset over 40 years.” This significantly…Sub-insular enlarged perivascular spaces are associated with gait symptom severity and tap response in normal pressure hydrocephalus
Objective: We aimed to present two novel neuroimaging biomarkers based on enlarged perivascular spaces (ePVS) of the sub-insular territory: the Hedgehog and Hedgehog-Halo (H-H) sign…the Degeneration of Locus Coeruleus and its Enhanced Causal Relationship to Neural Circuit in Parkinson’s Tremor
Objective: We aim to decode the neuroimaging features of LC in Parkinson's tremor. Background: Tremor is the primary symptom of Parkinson's disease (PD) and exhibits…Characterizing levodopa-induced dyskinesias using multimodal neuroimaging, clinical and behavioral measures
Objective: Our objective is to investigate potential differential modulation in motor and executive function networks among patients with LID, and to explore its correlation with…Structural and Functional Brain Alterations in Laryngeal Dystonia: A Coordinate-Based Activation Likelihood Estimation Meta-Analysis
Objective: Efforts to understand laryngeal dystonia (LD) pathophysiology using neuroimaging techniques have demonstrated altered brain structure and function in patients compared to healthy controls1-5. However,…Pisa Syndrome as an early presenting feature of Corticobasal Ganglionic degeneration [CBGD]
Objective: To describe Pisa syndrome as an early presenting feature of CBGD and add to literature on CBGD so that neurologists can suspect CBGD when…
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