Connectomic Analysis of SNc and VTA Projections to the Striatum and Cortex
Objective: To investigate the dopaminergic neural tracts of healthy individuals using Diffusion MRI on Human Connectome Project Data. Background: Classically, the DA system has been…In-vivo cholinergic basal forebrain degeneration and cognition in Parkinson’s disease: imaging results from the COPPADIS study
Objective: To assess associations between multimodal neuroimaging measures of cholinergic basal forebrain (CBF) integrity and cognition in a well-characterized multicentric cohort of Parkinson’s disease (PD)…The role of network connectivity in shaping the progression of cortical atrophy in Parkinson’s disease
Objective: We aimed to map the progression of cortical thinning and to test whether this pattern is constrained by network connectivity in the brain. Background:…Open-Source Tremor Tracking for MR-guided Focused Ultrasound (MRgFUS): An Objective Approach for Monitoring Treatments
Objective: To describe a novel system developed for real-time noninvasive monitoring of treatment efficacy in patients undergoing MR-guided Focused Ultrasound (MRgFUS) treatment for refractory tremor.…Safety of MRI performed with leads-only or fully implanted DBS system
Objective: To support the safety of the Infinity DBS system with MR Conditional labeling. Background: An international, multicenter, observational, prospective, single-arm, post-market clinical follow-up study…Longitudinal changes in nigral neuromelanin in early, levodopa-treated Parkinson’s disease
Objective: To assess longitudinal changes in neuromelanin (NM) content in the substantia nigra compacta (SNc) and its lateral-ventral subregion in Parkinson’s disease (PD). Background: NM-sensitive…Analysis of brain structural connectivity networks and white matter integrity in patients with early Parkinson’s disease: a longitudinal study
Objective: The objective of this study was to analyze the differences in structural connectivity and white matter (WM) microstructural integrity in people with early-PD over…Deep gray matter atrophy in MSA subtypes
Objective: To compare MRI parameters of atrophy in Multiple system atrophy (MSA) subtypes. Background: MSA is a rare adult-onset synucleinopathology that can be divided in…Patterns of Cortical Thinning in Patients with Parkinson’s Disease
Objective: To investigate patterns of cortical thickness that are associated with disease severity and response to levodopa. Background: Cortex affection is a neuropathological correlate of…Neuroanatomical signatures of genetic risk for Parkinson’s Disease in healthy adults
Objective: To determine whether there is a relationship between genetic risk for Parkinson’s disease (PD) and brain structure in healthy adults. Background: PD pathology begins…
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