Quantitative Susceptibility Mapping for Differential Diagnosis of Degenerative Parkinsonisms: A Comparison with Morphometric Indexes
Objective: To use a multimodal MRI approach for differential diagnosis of patients with degenerative parkinsonisms, comparing the diagnostic accuracy of Quantitative Susceptibility Mapping (QSM) data…Progression of cortical thinning in Parkinson’s disease
Objective: We sought to validate cortical thickness as an objective biomarker of Parkinson’s disease (PD) progression. Background: Cortical thickness analysis has been proposed as a…Direct Targeting of the VIM Nucleus during High Intensity Focused Ultrasound (HIFU) by Direct Visualization
Objective: To determine the “functional” target within VIM Nucleus of the Thalamus during HIFU with high field MRI. Background: Targeting of neuronal structures has been…White matter abnormalities and its relation to cognitive impairment in isolated Rapid Eye Movement sleep behavior disorder
Objective: To study white matter (WM) abnormalities and global cortical atrophy in isolated rapid eye movement sleep behavior disorder (IRBD) patients and its relation to cognitive…Spatiotemporal Changes in Substantia Nigra Neuromelanin Content from Prodromal to Clinical Parkinson’s Disease
Objective: To investigate the voxel-wise spatiotemporal changes in neuromelanin-sensitive MRI (NM-MRI) signal in the substantia nigra and their relation to clinical scores of disease severity…White matter microstructural abnormalities in tremor dominant and non-tremor dominant Parkinson’s disease
Objective: To explore differences in white matter microstructural integrity in tremor dominant and non-tremor dominant Parkinson’s disease (PD) using tract based spatial statistics (TBSS). Background:…Normative vs. patient-specific brain connectivity in Deep Brain Stimulation
Objective: The objective of this study was to compare similarities and differences between patient-specific, disease-matched and normative structural connectivity seeding from deep brain stimulation (DBS)…Striatal neurodegeneration in the presymptomatic phase of X-linked Dystonia-Parkinsonism
Objective: To identify structural brain changes in patients with X-linked dystonia-parkinsonism (XDP) and non-manifesting carriers of the TAF1 SVA retrotransposon insertion (NMC). Background: XDP is…Free Water in Corpus Callosum is Sensitive to Parkinson’s Disease-related Cognitive Decline
Objective: The objective of this study was to determine if the novel diffusion metric, free water (FW), from two-tensor modeling could sensitively identify microstructural alterations…Thalamic nuclei volumes and intrinsic thalamic network in motor subtype in Parkinson’s disease
Objective: The aim of this study is to investigate the alterations of thalamic nuclei volumes and intrinsic thalamic network in patients with de-novo PD according…
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