Role of clinical neuroimaging in X-linked dystonia-parkinsonism
Objective: To determine the inter- and intra-rater reliability of brain imaging in X-linked dystonia-parkinsonism (XDP). Background: XDP is a neurodegenerative movement disorder presenting with adult-onset…Sleep Disturbances in Essential Tremor: A pilot investigation of the related brain microstructural changes using diffusion tensor imaging
Objective: In this pilot exploratory study, we aimed to search possible related brain microstructural changes of sleep disturbances (SD) in essential tremor (ET) patients. Background:…Magnetic Resonance Spectroscopy Evaluation of Neuronal Integrity and Astrocytosis in a Phase 2 Study of Laquinimod as a Treatment for Huntington Disease (LEGATO-HD)
Objective: Evaluate the effect of laquinimod on putaminal and frontal white matter markers of neuronal integrity and astrocytosis using magnetic resonance spectroscopy (MRS) in patients…Nigral Iron Load as Diagnostic Parameter in Parkinson’s Disease
Objective: The aim of our study was to determine the diagnostic value of nigral iron depositions in PD, measured by iron specific MRI-techniques. Background: Nigral…Visual sensory processing is altered in myoclonus dystonia
Objective: The aim of the present study was to assess the temporal discrimination and motion processing in DYT-SGCE myoclonus-dystonia as well as its’ neuronal correlates…Incidental iron deposition in basal ganglia: does the pattern matter? Fifteen years’ experience in a tertiary care center.
Objective: We describe our series of patients with iron deposition in basal ganglia (IDBG) and hypothesize differences regarding the affected nuclei in patients with movement…Connectivity alterations in dopaminergic and cholinergic networks mediate cognitive performance in patients with Parkinson’s disease: a resting-state fMRI study
Objective: To explore changes in resting-state fMRI (rs-fMRI) functional connectivity networks in PD patients, in areas with prominent dopaminergic and cholinergic innervation. Background: The pathophysiology…Diagnostic potential of automated diffusion imaging for the differential diagnosis of multiple system atrophy and Parkinson’s disease
Objective: To evaluate the diagnostic potential of an automated diffusion imaging (DWI) analyses pipeline in separating patients with multiple system atrophy (MSA) and Parkinson’s disease…Ponto-cortical aberrations:Neural correlations for Hypomimia in PD
Objective: We team neuron, focused on analyzing progressive degeneration of neural structural connectivity of the tract from Brodmann area 4, part precentral gyrus to facial motor…Grey-matter volume changes underpinning irritability and aggression in early manifest Huntington’s disease
Objective: To explore grey-matter volume (GMV) differences between early-stage Huntington's disease (HD) patients with and without significant irritability/aggression symptoms (IAs) and to assess it association…
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