In-vivo free-water imaging and functional connectivity in a knock-in mouse model of DYT1 dystonia
Objective: To examine in-vivo functional connectivity and free-water diffusion imaging in dystonic mutant Tor1a knock-in (DYT1) and wild-type (WT) control mice. We test the hypothesis…Dementia in Parkinson’s disease is associated with increased diffusivity in amygdala and external capsule
Objective: To identify which regions are associated with dementia in Parkinson's disease (PD) brains. Background: Dementia is common in advanced PD and its early development…Olfaction and gray matter volume in Parkinson’s disease. A voxel-based morphometry study
Objective: To evaluate the relation between olfactory functioning and gray matter (GM) volume in patients with Parkinson's disease (PD). Background: Olfactory impairment is one of…The value of multi-slice computed tomography angiography in diagnosis of intracranial circulation in patients with vascular parkinsonism
Objective: The purpose of research was to evaluate the results of multislice computed tomographic angiography (MSCTA) in patients with vascular parkinsonism (VP) with stenotic lesions…Progressive atrophy of parahippocampal gyrus correlates with Hoehn & Yahr stages of Parkinson’s disease: A voxel based morphometric study
Objective: To determine the gray matter (GM) changes in different clinical stages of Parkinson's disease (PD) using Voxel Based Morphometry (VBM). Background: PD is a…Detecting brainstem changes in Parkinson’s disease using quantitative MRI
Objective: 1. Can brainstem changes be detected using quantitative MRI (qMRI). 2. How many subjects would be required to detecting changes in brainstem regions affected…Striatal postsynaptic dysfunction in X-linked dystonia-parkinsonism is associated with disease progression
Objective: To assess pre- and postsynaptic dopaminergic function in X-linked dystonia-parkinsonism (XDP). Background: X-linked dystonia-parkinsonism (XDP) is a neurodegenerative adult-onset movement disorder associated with striatal…Manual MRI morphometry in Parkinsonian syndromes
Objective: We investigated a large sample of Parkinsonian patients and healthy controls from five German academic medical centers with 3D MP-RAGE sequences on mainly 3T…Is levodopa-induced dyskinesia in Parkinson’s disease associated with increased blood brain barrier permeability and volumetric changes?
Objective: The aim of this study was to explore the angiogenetic hypothesis for Levodopa-induced-dyskinesia (LID) using advanced MRI methods in patients with Parkinson's disease (PD).…Cerebellar GABA in essential tremor and dystonic tremor: A MR spectroscopy study
Objective: To explore the role of GABA in the pathophysiology of ET and DT by using MR spectroscopy. Background: The mechanisms of tremor in ET…
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