Effectiveness of lead position with microelectrode recording based support vector machine for characterizing the sub-cortical-structures via deep brain stimulus in Parkinson`s disease
Objective: To develop artificial intelligence(AI) machine/deep learning techniques for processing/analyzing MER signals of STN which will help the surgical-team (neurologists,neurosurgeons) for deciding optimal location of…Human STN local field potentials recording and stimulation and sleep response in Parkinson’s disease after deep brain stimulation
Objective: To describe the continuous recording of STN local field potentials (LFPs) and their response to electrical stimulation and sleep in a Parkinson's disease (PD)…Intraoperative test objectively for discovering optimal electrode site for effective imaging (by eye) and bilateral STN-DBS stereotactic functional neurosurgery
Objective: To convolve the subject-specific (SS) electric-stimulus-field (ESF) with tremor-progress and progression quantified through accelerometer and stimulus-induced adverse side-effects (SIASE), exhibit visually (by eye) in…Objective study of intra operative test for discovering optimal electrode site for effective imaging and bilateral STN-DBS stereotactic functional neurosurgery
Objective: The objective is to examine the microrecording(MER, intra operative) and differentiate stimulus induced micro lesion effect on cardinal motor features of Parkinson's disease. Background:…The differential role of subthalamic and nigral neurons in gait control in Parkinson´s disease patients
Objective: The aim of the study was to identify and characterize subthalamic (STN) and nigral (SNr) neurons showing gait-related activity changes. 12 Parkinson’s disease (PD)…No evidence for early emotional processing in the subthalamic nucleus – a single neuron study
Objective: To provide evidence of early emotional processing at the single-neuron level in the STN. Background: A fast response to coarse threat signals in the…Development of an unsupervised analysis pipeline for human microelectrode recordings
Objective: Our aim is to develop computational tools that can assist clinical decision in Deep Brain Stimulation (DBS) for Parkinson's disease (PD) using intraoperative microelectrode…Is Microelectrode Recording mandatory for Deep Brain Stimulation in Parkinson’s disease?
Objective: To find whether microelectrode recording (MER) is mandatory for deep brain stimulation (DBS) in Parkinson’s disease. Background: DBS is traditionally done using MER guidance.…A functional micro-electrode mapping of ventral thalamus in Essential Tremor
Objective: Understanding the pathomechanisms of Essential Tremor (ET) with higher spatial and temporal precision is of important clinical relevance. While the efficiency of Deep Brain…Patterns of rhythmic single unit activity of the subthalamic nucleus in patients with Parkinson’s disease
Objective: The study of rhythmic neuronal activity is of great interest as they may have implications for pathophysiological mechanisms of PD. The aim of this…