Transcriptome modification of anodal transcranial direct current stimulation in transgenic Parkinson’s disease mouse model
Objective: We tried to investigate the impact of tDCS on mRNA and microRNA expression in striatum and substantia nigra of transgenic mouse model of PD.…α-Synuclein induced dopaminergic neurons mitochondrial dysfunction via cytochrome c oxidase subunit 2
Objective: To investigate the mechanism of how α-Syn injure the the dopaminergic neurons. Background: The misfolded α-Synuclein(α-Syn) transferring from cells to cells as prion protein…Mitochondrial DNA variants function as potential genetic risk factors for Parkinson disease
Objective: To understand whether mtDNA variants contribute to the susceptibility to sporadic PD. Background: It is well-recognized that mitochondrial (mt) dysfunction is involved in the…Two new cases of a novel ovario-leukodystrophy related to AARS2 mutation from Korea
Objective: Progressive leukoencephalopathy with primary ovarian failure (LKENP; OMIM # 615889) is a novel ovario-leukodystophy caused by compound heterozygote mutations in the AARS2 gene of…Mitochondrial-nuclear interplay in single respiratory chain-deficient Parkinson’s disease neurons
Objective: To explore the role of the mitochondrial DNA (mtDNA) in the development of respiratory chain complex (CI-IV) deficiencies in the substantia nigra (SN) of…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.