Pilot economic evaluation of Personal KinetiGraph (PKG) for management of Parkinson’s disease in Australia
Objective: To determine the potential cost savings and quality of life gains with the Personal KinetiGraph (PKG) in the management of patients with Parkinson’s disease…Influence of dopamine deficiency on interhemispheric crosstalk in Parkinson’s disease
Objective: To identify the significance of dopaminergic depletion in Parkinson’s disease (PD) on interhemispheric crosstalk using a complex bimanual tapping task. Background: Dopamine deficiency in…A randomized, double-blind, placebo-controlled Phase II Efficacy and Safety Study of the PDE10A inhibitor PF-02545920 in Huntington Disease (AMARYLLIS)
Objective: To assess efficacy on motor function, safety and tolerability of the phosphodiesterase-10A inhibitor PF-02545920 in Huntington disease (HD). Conclusion: PF-02545920 was generally safe and…Costs and outcomes for Parkinson’s disease patients who have their management adjusted by Personal KinetiGraph (PKG)
Objective: To quantify the potential cost savings and quality adjusted life years (QALYs) gained for people with Parkinson’s disease in Australia whose oral therapy was…Naturalistic-based UPDRS-III Minimal Clinically Important Difference (MCID) in early PD
Objective: To find the MCID of the UPDRS-III subscale in early PD subjects, when started on a new dopaminergic drug. Background: The concept of Minimally…Speech in Huntington’s Disease
Objective: To review existing literature on speech function in Huntington’s disease (HD) across the disease spectrum. Background: Impairment in speech production affects the majority of…Feasibility of a multi-sensor data fusion method for assessment of Parkinson’s disease motor symptoms
Objective: To assess the feasibility of measuring Parkinson’s disease (PD) motor symptoms with a multi-sensor data fusion method. More specifically, the aim is to assess…Neuronal correlates of oculomotor alterations in Huntington’s disease. A 18-FDG PET study
Objective: To explore the neuroanatomical correlates of the oculomotor abnormalities in Huntington's disease (HD) through a 18-FDG PET study Background: Alterations of the oculomotor function…Safety and efficacy of high definition tDCS for proprioception and balance in Parkinson’s disease: A pilot randomised trial
Objective: To determine: 1. Is HD-tDCS safe and well-tolerated in PD? 2. Does combined HD-tDCS and physical exercise improve proprioception and balance in PD? Background:…Ankle proprioception and postural instability in Parkinson’s disease
Objective: To determine: 1. Is there a correlation between central and peripheral proprioception in Parkinson’s disease? 2. Does postural instability increase with lack of vision…
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