Use digital sensor and deep learning to evaluate motor performance in the D1PAM (LY3154207) phase 1B Parkinson’s disease clinical trial
Objective: This study aims to test the feasibility of using digital tools to evaluate motor performance in a Parkinson’s disease clinical trial. Background: Modern smartphones…Objective assessment of motor states in Parkinson’s disease using partial least squares and smartphone data
Objective: In this study, we will investigate the behaviour of Partial Least Squares (PLS) regression for dimension reduction and prediction of motor states of Parkinson’s…Intraoperative test stimulation of the subthalamic nucleus reduces the search space for chronic stimulation settings in Parkinson’s disease
Objective: To determine whether intraoperative test stimulation is indicative of postoperative stimulation results. Background: It is unknown whether intraoperative testing during awake Deep Brain Stimulation…Opicapone added to safinamide in patients affected by Parkinson’s disease for better controlling motor fluctuations
Objective: The aim of this clinical observation was to verify the sparing of levodopa in patients affected by Parkinson's disease who already started safinamide treatment for…An Internet of Things system for patient empowerment: a case study on measuring patients’ understanding of causal relationships between symptoms and behaviour
Objective: To evaluate the ability of patients to understand causal relationships between disease symptoms and behaviour presented from synthetic representative cases using the system. Secondary…“Poised for Parkinson’s”: Group classes in Alexander technique for managing symptoms of Parkinson’s disease
Objective: To develop and test a group course using Alexander technique (AT) principles to improve functional mobility and quality of life for people living with…Effect of finger rhythmic movement training on freezing of gait in Parkinson’s disease patients: A study protocol
Objective: To investigate the effect of finger rhythmic movement (FRM) training on freezing of gait (FOG) in Parkinson's disease (PD) patients. Background: External cues such…Auditory rhythmic cueing changes motor control during walking in Parkinson’s disease
Objective: (1) Evaluate changes in gait motor activity patterns induced by auditory rhythmic cueing in people with PD. (2) Investigate change in gait parameters. Background:…Internet of Things for Empowerment and Improved Treatment of Patients with Parkinson’s Disease
Objective: This study aims to assess the effects of patient-directed feedback from remote symptom, medication, and disease activity monitoring on patient empowerment and treatment in…Efficacy and safety of safinamide as a levodopa adjunct in patients with parkinson disease and motor fluctuations: A systematic review of randomized controlled trials
Objective: To assess the efficacy and safety of safinamide as an add-on therapy to levodopa in Parkinson patients. Background: Long-term use of levodopa is associated…
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