Association between fine motor function and brain structure: Findings from the population-based Rhineland Study
Objective: To examine the relation between brain structure and fine motor function across adult lifespan in a large cohort study. Background: Decreased fine motor function…Education and the motor effects of dopamine loss in Parkinson’s disease
Objective: To examine the relation between education and dopamine signal loss in PD. Background: In support of the cognitive reserve concept, it has consistently been…Deep brain stimulation modulates subthalamic beta bursts related to movement velocity adjustments in Parkinson’s disease
Objective: The aim of this study was to investigate the role of subthalamic beta bursts for dynamic control of precise drawing movements. Background: The performance…Exploring patient-physician communication in Parkinson’s disease management: a qualitative analysis
Objective: To explore the unmet needs in patient-physician communication from different perspective.To explore the unmet needs in patient-physician communication from different perspective. Background: Patient-physician communication…Motor control of finger individuation and strength in patients with Parkinson’s disease and Spinocerebellar Ataxia type 12
Objective: Compare finger individuation (FI) and maximum finger strength in healthy control, patients with Parkinson’s Disease (PD) and Spinocerebellar ataxia type12 (SCA12). We also examined…Repurposing the MDS-UPDRS part III for early-stage Parkinson’s disease: Supportive evidence for a bradykinesia and rigidity specific sub-score
Objective: Characterize specific motor signs and their impact on the daily life of people with early-stage Parkinson’s disease (PD) before initiation of symptomatic treatment (ST)…Alterations of gait as an early marker of incipient alpha-synucleinopathy
Objective: To investigate early motor signs of α-synucleinopathies in patients with isolated REM sleep behavior disorder (iRBD) using gait analysis. Background: iRBD is an early…WATCH-PD: Longitudinal Digital Assessments in Early Parkinson’s Disease
Objective: To provide a longitudinal profile of early Parkinson’s disease (PD) progression using clinical and digital measures, and to evaluate the extent to which digital…Enhanced sensitivity to bradykinesia progression using digital health technologies in early Parkinson’s disease
Objective: To evaluate the sensitivity of digital biomarkers of bradykinesia to longitudinal progression relative to MDS-UPDRS sub-scores in early-stage Parkinson’s disease (PD). Background: It is…Connectivity Profile for Deep Brain Stimulation in Early-Stage Parkinson’s Disease
Objective: To describe the relationship between stimulation location and motor progression for the deep brain stimulation (DBS) in early-stage Parkinson’s disease (PD) pilot trial cohort…
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