Beta oscillatory changes during practice and retention of motor skills in healthy subjects and patients with PD
Objective: The objective is to define the relationship between increase in beta oscillatory changes with practice and retention of motor skills in normal healthy subject…Cortical phase amplitude coupling (PAC) identifies patterns in clinical states of Parkinson’s disease (PD) using magnetoencephalography (MEG)
Objective: To apply pattern recognition algorithms to identify changes in cortical phase amplitude coupling (PAC) responses derived from PD subjects while off and on levodopa/carbidopa…Investigation of the influence of the parieto-premotor network on the motor cortex in writer’s cramp using transcranial magnetic stimulation
Objective: We aimed to study the influence of the parieto-premotor network on the motor cortex in patients with writer's cramp. Background: The parietal and premotor…Deep brain stimulation of the locomotor mesencephalic region in rats with lesioned sensorimotor cortex: A model of functional motor recovery after stroke
Objective: To evaluate whether electrical stimulation of the locomotor mesencephalic region (LMR) in rats with lesioned sensorimotor cortex improves (1) locomotion assessed by the CatWalk…The role of active rehabilitation measures, for maintaining the quality of life of patients after stroke with movement disorders in the general practice conditions
Objective: Assessment of the impact of active rehabilitation measures on quality of life of patients after stroke with movement disorders in primary health care. Background:…Staging and clinical correlates of cortical thinning in Parkinson’s disease
Objective: By using a novel disease staging model to investigate the progression and clinical associations of cortical thinning in Parkinson's disease (PD) patients. Background: The…Preclinical evaluation of sub-anesthetic ketamine infusion to reduce L-DOPA-induced dyskinesias: Is it a ‘chemical’ DBS?
Objective: To evaluate mechanism of long-term activity of sub-anesthetic ketamine infusion to reduce L-DOPA-induced dyskinesias (LID). Background: Ketamine is an anesthetic that, when administered as…The effect of STN-DBS on movement initiation control is modulated by the noradrenergic system: Evidence of an interaction from a combined pharmacological/DBS/EEG study
Objective: Assessing the role of the noradrenergic system underlying the effect of subthalamic nucleus stimulation (STN-DBS) on akinesia. Background: Slowness in movement initiation, associated with…Patient case reports supporting a long-term effect of sub-anesthetic ketamine infusion in reducing L-DOPA-induced dyskinesias
Objective: To evaluate possible long-term anti-dyskinetic activity of low-dose sub-anesthetic ketamine infusion from a retrospective chart review. Background: Repurposing drugs that have already been proven…Modulation of thalamocortical network dynamics via deep brain stimulation in humans with Tourette syndrome
Objective: To (1) investigate the impact on thalamocortical network dynamics in response to low frequency and high frequency deep brain stimulation and (2) uncover the…
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