EAGLE: Protocol for a Phase 3 Study to Evaluate the Efficacy and Safety of Two Mobile Applications Combined with Immediate-Release CD/LD for the Management of Idiopathic Parkinson’s Disease
Objective: To evaluate the efficacy and safety of Hybridopa A and Hybridopa B, combination products of immediate-release carbidopa/levodopa (IR CD/LD) and therapeutic mobile applications, in adults with idiopathic Parkinson’s disease (PD) on a…A Pragmatic Phenotype-Guided Algorithm for Constipation in Parkinson’s Disease
Objective: Evaluate the effect of a structured Mediterranean-style high fiber diet as the cornerstone of treatment with additional therapies layered when needed (FIBER-MED), using a…Untangling the Web of Fall Risk in Parkinson’s Disease Through Machine Learning
Objective: to use machine learning on detailed clinical, cognitive, balance, and gait data to identify which features best predict falls risk in people with Parkinson’s…Diagnostic Test Utilization and Timing in a Multidisciplinary Gastrointestinal Symptom Clinic: Insights from the Parkinson’s Research and Integrated Support Model (PRISM) Clinic
Objective: This study evaluates the diagnostic yield of an algorithm-based approach implemented in the Parkinson’s Research and Integrated Support Model (PRISM) clinic [1]. Background: Gastrointestinal…Comparability of Smartphone App and Booth Recordings for Robust Acoustic Speech Monitoring in Parkinson’s Disease
Objective: To assess the technical equivalence and scalability of remote app-based recordings against gold-standard laboratory conditions to identify reliable speech features suitable for longitudinal monitoring…Weight and Body Mass Index Changes in Parkinson’s Disease and Their Association with Disease Progression: A Two-Year Longitudinal Study
Objective: To analyze disease progression in relation to changes in body weight (BW) and body mass index (BMI) over two years in Parkinson’s disease (PD)…Identifying Informative Speech Tasks for Detecting Clinically Relevant Changes in Parkinson’s Disease
Objective: To identify the most informative speech tasks for detecting clinically relevant speech changes in Parkinson’s Disease (PD) and to develop a streamlined, data-driven assessment…Assessing an inclusive online lifestyle-based intervention program that supports British Columbians living with chronic neurological conditions, their care partners and healthy agers
Objective: To evaluate the implementation, feasibility, and perceived benefits of the BC Brain Wellness Program (BCBWP), an interdisciplinary lifestyle-based intervention designed to support the quality of…Personalized Rhythmic Cueing Differentially Improves Straight Walking and Turning in Parkinson’s Disease
Objective: To evaluate the effects of different rhythmic auditory stimulation (RAS) strategies on straight walking and turning in Parkinson’s disease (PD) and identify clinical predictors…Implementing Adaptive Deep Brain Stimulation in Parkinson’s Disease: A Multimodal Mixed-Methods Evaluation of a Pragmatic Clinical Workflow
Objective: The objective of this study is to evaluate a pragmatic clinical workflow and real-world implementation of adaptive Deep Brain Stimulation (aDBS) through integrated clinical,…
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