Identifying Informative Speech Tasks for Detecting Clinically Relevant Changes in Parkinson’s Disease
Objective: To identify the most informative speech tasks for detecting clinically relevant speech changes in Parkinson’s Disease (PD) and to develop a streamlined, data-driven assessment…Assessing an inclusive online lifestyle-based intervention program that supports British Columbians living with chronic neurological conditions, their care partners and healthy agers
Objective: To evaluate the implementation, feasibility, and perceived benefits of the BC Brain Wellness Program (BCBWP), an interdisciplinary lifestyle-based intervention designed to support the quality of…Personalized Rhythmic Cueing Differentially Improves Straight Walking and Turning in Parkinson’s Disease
Objective: To evaluate the effects of different rhythmic auditory stimulation (RAS) strategies on straight walking and turning in Parkinson’s disease (PD) and identify clinical predictors…Implementing Adaptive Deep Brain Stimulation in Parkinson’s Disease: A Multimodal Mixed-Methods Evaluation of a Pragmatic Clinical Workflow
Objective: The objective of this study is to evaluate a pragmatic clinical workflow and real-world implementation of adaptive Deep Brain Stimulation (aDBS) through integrated clinical,…Understanding the Impact of the Small Scale Levodopa-Entacapone-Carbidopa-Intestinal-Gel Pump on Everyday Experiences of People Living with Parkinson’s Disease: A Mixed-Methods Evaluation
Objective: This study aims to qualitatively evaluate the impact of switching from the conventional Levodopa-Carbidopa-Intestinal-Gel (LCIG) pump to the smaller sized Levodopa-Entacapone-Carbidopa-Intestinal-Gel (LECIG) pump on…Outpatient Multidisciplinary Care for Parkinson’s Disease: A Narrative Review of Care Models and Outcomes
Objective: To summarize best practices in outpatient multidisciplinary care models for Parkinson’s disease (PD), focusing on team composition, care coordination, interventions, and patient-centered outcomes. Background:…Efficacy of Combining Outpatient Palliative Care with Standard Care on Quality of Life and Caregiver Burden in Atypical Parkinsonian Syndrome – A Randomised Controlled Trial
Objective: This study evaluates the effectiveness of structured outpatient palliative care combined with standard care compared to standard care alone at 3 and 6 months…Psychiatric Profile of Screen Failures for Deep Brain Stimulation (DBS) Candidacy Evaluation: A Retrospective Cohort Study at a large tertiary referral center
Objective: To characterize psychiatric profiles of screen failures during evaluation for DBS candidacy for Parkinson disease (PD), dystonia or essential tremor. Background: DBS is FDA-approved…Repurposing Rifabutin for Neuro-Metabolic Disorders: AMPK-PGC-1α-Driven Mitochondrial Protection in Diabetes Associated Parkinsonism
Objective: To assess the role of rifabutin in restoring mitochondrial function and energy balance through modulation of the AMPK–PGC-1α signaling pathway in diabetes-related Parkinsonism. Background:…Development of a Web Based Neuro Recovery Roadmap Prototype for Visualizing and Tracking Multidisciplinary Rehabilitation in Movement Disorders
Objective: To design a dual-portal Software-as-a-Service (SaaS) platform to facilitate asynchronous monitoring, enhance ecological momentary assessment, and visualize multidisciplinary neurorestorative protocols in movement disorder patients.…
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