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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Multiple system atrophy(MSA): Etiology and Pathogenesis"

  • 2018 International Congress

    Cerebrospinal fluid levels of cytokines in multiple system atrophy: A cross-sectional study of the atalan msa registry (CMSAR)

    Y. Compta, S. Dias, M. Pulido-Salgado, D. Giraldo, A. Pérez-Soriano, M. Fernández, A. Cámara, P. Bravo, E. Muñoz, J. Saura, MJ. Marti (Barcelona, Spain)

    Objective: To compare the cerebrospinal fluid (CSF) levels of 38 cytokines in multiple system atrophy (MSA) patients vs. control and Parkinson’s disease (PD) subjects. Background:…
  • 2018 International Congress

    Patterns of dopamine transporter imaging in subtypes of Multiple System Atrophy

    F.T. Liu, L.L. Bu, Y.J. Yang, P. Wu, C.T. Zuo, J. Wang (Shanghai, China)

    Objective: To investigate the differences in the pattern of striatal (caudate and putamen) dopamine transporter(DAT) loss in a multiple system atrophy (MSA) cohort, based on…
  • 2017 International Congress

    α-Synuclein Preformed Fibrils Induce Disruption of Myelin Basic Protein Expression in Primary Oligodendrocyte Culture; Deciphering Glial Pathology in Multiple System Atrophy

    S. Kaji, T. Maki, N. Uemura, R. Takahashi (Kyoto, Japan)

    Objective: This research focuses on the impact of extracellular α-synuclein preformed fibrils (α-syn PFFs) on oligodendrocytes (OLGs) as a potential contributor exacerbating the pathology of…
  • 2017 International Congress

    Mutational analysis of COQ2 in Chinese patients with multiple-system atrophy

    J. Zhang, Y. Hao, Y. Chen, M. Ding, X. Zhang, W. Gu (Beijing, China)

    Objective: To investigate the involvement of COQ2 variants in Chinese sporadic cases with multiple-system atrophy. Background: Multiple-system atrophy (MSA) is a rapidly progressive neurodegenerative disease…
  • 2017 International Congress

    Gut Microbiota in Multiple System Atrophy

    A.H. Tan, C.W. Chong, S.-L. Song, C.S.-J. Teh, I.K.-S. Yap, M.F. Loke, Y.Q. Tan, H.S. Yong, S. Mahadeva, A.E. Lang, S.-Y. Lim (Kuala Lumpur, Malaysia)

    Objective: To investigate the gut microbiome and metabolome in MSA Background: Experimental models of prion-like cell-to-cell transfer of alpha-synuclein(AS) and its ability to spread from the…
  • 2017 International Congress

    Evaluation of mitochondrial dysfunction in fibroblasts and iPSC-derived dopaminergic neurons of patients affected by Multiple System Atrophy

    G. Monzio Compagnoni, E. Frattini, F. Fortunato, D. Ronchi, A. Bordoni, M. Garbellini, S. Salani, M. Guida, N. Bresolin, S. Corti, G.P. Comi, A. Di Fonzo (Milano, Italy)

    Objective: The aim of the present study is to investigate mitochondrial functioning in fibroblasts and iPSC-derived dopaminergic neurons of patients affected by Multiple System Atrophy…
  • 2017 International Congress

    Are a „mathematical brain“ and early childhood adverse events possible risk factors that contribute to Progressive Supranuclear Palsy?

    S. Lorenzl (Hausham, Germany)

    Objective: To evaluate possible risk factors for the development of Progressive Supranuclear Palsy (PSP). Background: Risk factors for the development of neurodegenerative brain disorders are…
  • 2016 International Congress

    The Catalan multiple system atrophy-registry (CMSAR)

    F. Antonelli, E. Muñoz, J. Pagonabarraga, J. Hernández-Vara, A. Bayes, O. de Fabregues, F. Valldeoriola, E. Tolosa, Y. Compta, M. Ezquerra, R. Fernandez, M. Calopa, S. Jauma, M. Pujol, V. Puente, A. Cámara, L. Planellas, M.J. Martí (Barcelona, Spain)

    Objective: To collect comprehensive and standardized clinical data and to create a repository of biological samples and cell lines from probable and possible MSA patients…
  • 2016 International Congress

    Can deep brain stimulation implantation cause multiple system atrophy? A retrospective review of MSA patients

    E.A. Coon, B.T. Klassen, J.E. Ahlskog, P.A. Low, W. Singer (Rochester, MN, USA)

    Objective: To evaluate whether implantation of deep brain stimulation (DBS) could lead to multiple system atrophy (MSA). Background: Recent studies regarding the transmissibility of alpha-synuclein…
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