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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Multiple system atrophy(MSA): Pathophysiology"

  • MDS Virtual Congress 2020

    CHCHD2 mRNA levels in erythrocyte are reduced in patients with multiple system atrophy

    G.l Liu, X.d Liu, T. Feng (Beijing, China)

    Objective: To investigate CHCHD2 mRNA expression of erythrocyte in patients with multiple system atrophy (MSA). Background: Coiled-coil-helix-coiledcoil-helix domain containing 2 (CHCHD2) are reported to be associate with…
  • MDS Virtual Congress 2020

    Brain 5-HT1 receptor binding in multiple system atrophy: A [18F]-MPPF PET study

    M. Meyer, I. Sibon, F. Lamarre, J. Asselineau, A. Foubert-Samier, J. Mazère, A. Delamarre, O. Rascol, A. Pavy-Le Traon, F. Tison, P. Fernandez, W. Meissner (Bordeaux, France)

    Objective: The primary objective was to compare brain 5-HT1a receptor binding between patients with multiple system atrophy (MSA) and healthy controls (HC). The secondary objectives…
  • MDS Virtual Congress 2020

    GCI-induced neurodegeneration and synucleinopathy in non-human primates

    M. Teil, S. Dovero, M.L Artocarena, M. Bourdenx, G. Porras, B. Mollenhauer, M.T Herrero, M. Vila, J. Obeso, B. Dehay, E. Bezard (Bordeaux, France)

    Objective: This study aimed at determining the potential to induce MSA pathology in non-human primates. Background: Aggregation of alpha-synuclein has been implicated in several neurodegenerative…
  • 2019 International Congress

    Abnormal respiratory rate and patterns in MSA

    E. Driver-Dunckley, B. Goodman (Scottsdale, AZ, USA)

    Objective: To evaluate respiratory rate and patterns in patients with Multiple Systems Atrophy (MSA). Background: One of the primary clinical features of multiple system atrophy…
  • 2019 International Congress

    Speculation on the timing of iron deposition in the putamen of patients with multiple system atrophy: multimodal MRI study

    MJ. Lee, JH. Lee (Yangsan-Si, Republic of Korea)

    Objective: We sought to investigate the temporal pattern of iron deposition in  the putamen of patients with multiple system atrophy (MSA)  by calculating conditional probabilities…
  • 2019 International Congress

    Unraveling biological processes implicated in MSA and PD by transcriptomic analysis

    A. Perez-Soriano, M. Arnal, D. Giraldo, M. Fernandez, T. Botta-Orfila, Y. Compta, R. Fernández-Santiago, M. Ezquerra, D. Tartaglia, MJ. Martí (Barcelona, Spain)

    Objective: To find differential biological processes between synucleinopathies (MSA and PD). Background: Multiple system atrophy (MSA) is an oligodendroglial sinucleinopathy that is often misdiagnosed as…
  • 2019 International Congress

    Differences in resting state fMRI distinguish multiple system atrophy and Parkinson disease

    A. Peterson, E. Dayan, N. Browner, D. Drazheva, M. Sklerov (Chapel Hill, NC, USA)

    Objective: To investigate whether functional connectivity of the hypothalamus can distinguish multiple system atrophy from Parkinson disease. Background: Multiple system atrophy parkinsonian subtype (MSA-P) and…
  • 2019 International Congress

    Abnormal metabolic brain network in multiple system atrophy and progressive supranuclear palsy: a replication on a new European cohort

    T. Rus, E. Rebec, P. Tomše, A. Studen, M. Grmek, C. Tang, D. Eidelberg, M. Trošt (Ljubljana, Slovenia)

    Objective: To identify characteristic metabolic brain patterns specific for multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) in a new cohort of patients and…
  • 2019 International Congress

    Increased lysosphingolipids levels in blood of patients with multiple system atrophy

    K. Senkevich, G. Baydakova, A. Emelyanov, M. Nikolaev, A. Kopytova, I. Miliukhina, E. Gracheva, A. Kudrevatykh, I. Krasakov, L. Khublarova, I. Fursova, Y. Irishina, N. Zalutskaya, Y. Beltseva, E. Zakharova, S. Pchelina (Saint-Petersburg, Russian Federation)

    Objective: To estimate activity of lysosomal enzymes and lysosphingolipids concentration in dry blood spot of patients with synuleinopathies: Parkinson’s disease (PD), dementia with Lewy bodies…
  • 2019 International Congress

    Hypothalamic functional connectivity correlates with autonomic symptom burden in patients with Multiple System Atrophy

    M. Sklerov, N. Browner, D. Drazheva, E. Dayan (Chapel Hill, NC, USA)

    Objective: To investigate the association between autonomic symptom burden and hypothalamic functional connectivity in patients with MSA. Background: Multiple system atrophy (MSA) is a progressive…
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