Co-administration of levodopa and zonisamide reduces the serotonin transporter expression in a rat model of Parkinson’s disease
Objective: To investigate the change of striatal serotonergic system according to the administration of levodopa and zonisamide (ZNS) on the striatal serotonergic system, we analyzed the…Motor learning and long duration response to levodopa in Parkinson’s disease.
Objective: To define the role of long-duration response (LDR) in motor learning, evaluating neurophysiological parameters in patients affected by Parkinson’s disease (PD) with and without…Hypermethylation of PGC-1α in peripheral blood leukocytes of patients with Parkinson’s disease
Objective: We aimed to explore the hypothesis that the PGC-1α variants are associated with its promoter methylations level thus affecting the PGC-1α mRNA expression. We…Unilateral increase of blink reflex recovery cycle in drug-naive hemiparkinson syndrome.
Objective: We assessed R2 Blink Reflex Recovery Cycle (R2 BRRC) in drug-naive Parkinson’s disease (PD) patients with unilateral tremor and/or rigidity, diagnosed as hemiparkinson syndrome,…Retinal layer thinning in de novo Parkinson’s disease
Objective: To identify and substantiate the occurrence, extent and location of retinal degeneration in de novo Parkinson’s disease patients (PD) compared to primary open angle…Freezer or non-freezer: what is in between?
Objective: This study aimed to characterize turning performance and clinical characteristics in people with definite, probable or no Freezing of Gait (FoG) in a cohort…Comparison of LFP-physiomarkers for DBS programming
Objective: To evaluate clinical usability of LFP(local field potentials)-physiomarkers and lead localisation for selection of suitable DBS electrode configurations. Background: Selection of optimal contacts in…Adult-onset stereotypy — An atypical presentation of frontotemporal dementia
Objective: Describe a case of adult-onset stereotypy with abulia. Background: Stereotypy is a non-goal directed but distractible behavior repeated continuously. While common in the pediatric…Study of eye movements as a tool in the diagnosis hereditary ataxias
Objective: To study ocular movements (ocular pursuit, nystagmus and saccades) in the most frequent ataxias (SCA2, SCA3 and Friedreich's ataxia), to find out which variables…Oscillaotory activity in the globus pallidus internus in patients with Parkinson’s disease
Objective: To quantify the characteristics of oscillatory neurons in the GPi in patients with PD. Background: Abnormal oscillatory activity has been predicted to play a…
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