Glial interaction with Parkinsonian disorders biomarkers: alpha-synuclein, dopaminergic dysfunction and clinical stages
Objective: We aim to investigated the relationship between glial markers and Parkinson's disease. Background: Neuronal α-Synuclein Disease (NSD) has recently been proposed as a framework for…Parkinson’s disease motor phenotypes delineated by pallidal and subthalamic neurophysiology and machine learning
Objective: The objective of this study was to develop a machine learning (ML) algorithm capable of predicting motor phenotypes in Parkinson's disease (PD) using intraoperative…Subthalamic β frequency oscillatory activity is modulated by self-paced wrist movement
Objective: To explore whether subthalamic β oscillatory neurons are associated with the initiation of voluntary movement in patients with Parkinson’s disease (PD). Background: The basal…Towards automated deep brain stimulation programming using neurophysiology and artificial intelligence
Objective: To develop a machine learning (ML) algorithm capable of predicting the optimal deep brain stimulation (DBS) contact based on neurophysiology. Background: DBS is an…TMS-EEG Provides Objective Neurophysiological Measures of Motor Fluctuations in Parkinson’s Disease
Objective: To assess the correlates TMS evoked potentials (TEPs) measurements changes representing interhemispheric transmission to the change in motor symptoms in 'off' versus 'on' states.…Frontal and Motor TMS Evoked Potentials Predict Response to Ventriculoperitoneal Shunt in NPH
Objective: Assess the ability of neurophysiological measure of TMS evoked potentials to predicts response to shunting in NPH. Background: NPH is an age-related condition of…Oculomotor Differences in PARK2 PD: a Study of Structured and Unstructured Eye Movements in an Irish Genetic Cohort
Objective: To identify and measure how eye movements differ between biallelic PARK2 carriers, carriers of a single PARK2 variant and non-carriers using structured and unstructured…Anal Sphincter EMG changes can Progress over Time and can be considered as a Prognostic Marker in MSA
Objective: To assess the usefulness of repeat anal sphincter EMG for prognostication of MSA Background: External anal sphincter (EAS) electromyography (EMG) is an established method…Value of local field potential-based deep brain stimulation programming in Parkinson’s disease
Objective: To report preliminary data on the utility of local field potential(LFP)-based programming in bilateral subthalamic nucleus(STN) deep brain stimulation(DBS) for Parkinson’s disease(PD). Background: Current…Voluntariness in painful legs moving toes: insights form neurophysiological studies
Objective: Neurophysiological studies on painful legs moving toes (PLMT) syndrome are limited. This study aims to characterize the neurophysiological features of PLMT and assess whether…
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