Cerebellar learning and its modifiability by alcohol in myoclonus-dystonia
Objective: To investigate cerebellar learning and its modifiability by alcohol in SGCE mutation-positive M-D using eye blink conditioning (EBC). Background: M-D is characterized by generalized…Astroglia exert a neuro-protective role in Parkinson’s disease by reducing oxygen stress through dopamine-induced activation of the pentose-phosphate pathway
Objective: Although dopaminergic neurons themselves take up most of the released dopamine (DA), a part of the DA appears to be taken up by astroglia.…Single unit activity of medial thalamus during goal-directed motor and cognitive behavior in patients with cervical dystonia
Objective: To 1) study neuronal activity of medial thalamic nuclei (MD, CM-Pf) and its role in cognitive and motor human activity and 2) evaluate neuronal…Investigating the plastic effects of rapid paired associative stimulation in dystonia
Objective: To investigate the effects of rapid paired associative stimulation (PAS) in organic and psychogenic dystonia to see if this technique can differentiate them. Background:…Localization and functional study of synaptic vesicle protein synaptogyrin-3 (SYNGR3) on dopaminergic neuronal system
Objective: To investigate (1) the intracellular localization of SYNGR3 and its interaction with dopamine transporter (DAT); (2) how expression of SYNGR3 in neurons affects dopamine…Automatic event-detection for the neurophysiological evaluation of voluntary and involuntary movements
Objective: This project aims at creating a tool for automatic EMG event- detection to support clinicians in this process. Background: Neurophysiological evaluation of voluntary and…AMP kinase regulates ligand-gated K-ATP channels in substantia nigra dopamine neurons
Objective: To characterize the effect of AMP-activated protein kinase (AMPK) on ATP-sensitive K+ (K-ATP) channels on substantia nigra compacta (SNC) dopamine neurons in slices of…A whole brain anatomical network model and its application in PD research
Objective: To build a frame of whole brain anatomical network for incorporating different data from different studies with different brain parcellations and resolutions, to evaluate…Nigrostriatal degeneration and serum BDNF levels in patients with “de novo” untreated Parkinson’s disease
Objective: To evaluate serum Brain-Derived NeurotrophicFactor(BDNF) levels in “de novo” untreated Parkinson's disease (PD) patients and their relationship to nigrostriatal degeneration measured with [123I]FP-CIT SPECT.…Proprioceptive training as a means to enhance sensorimotor function in Parkinson’s disease
Objective: To identify whether proprioceptive function in Parkinson's disease (PD) can be enhanced by specialized visuomotor training that emphasizes precise movements and determine if such…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.