Towards a Machine Learning Based Classification System for Hyperkinetic Movement Disorders: Generating a Neurophysiological Feature Set
Objective: Generating a set of significant neurophysiological features to build a machine learning based diagnostic system for hyperkinetic movement disorders. Background: Hyperkinetic movement disorders cause…Determination of metabotropic glutamate receptor 2/3 distribution with [3H]-LY-341,495 in Parkinson’s disease patients with visual hallucinations
Objective: To determine the distribution and levels of metabotropic glutamate 2/3 (mGlu2/3) receptors in brain tissue from patients with Parkinson’s disease (PD) with visual hallucinations (VHs).…Longitudinal study of clinical and neurophysiological features of essential tremor
Objective: This study investigates how motor and non-motor manifestations of essential tremor (ET) progress over time. Background: ET is a common and heterogeneous movement disorder…Evoked resonant neural activity within the dorsolateral subthalamic nucleus as a biomarker for the targeting of deep brain stimulation for Parkinson’s disease
Objective: The objective of the study was to determine the anatomical localisation of evoked resonant neural activity (ERNA), which is being investigated as a potential…Gait declines faster over time in people with Parkinson’s disease converting to a freezing of gait phenotype
Objective: To monitor gait progression in people with Parkinson’s disease (PwPD) who convert from a non-freezing (noFOG) to a freezing of gait (FOG) phenotype. Background:…Modulation of the mesencephalic locomotor region activity during gait in parkinson’s disease patients
Objective: Deciphering the role of the MLR in gait and balance disorders in PD patients Background: Lesion or dysfunction of the MLR, including the Pedunculopontine…Perceive: A data extraction and analysis toolbox for brain signals from sensing enabled deep brain stimulators
Objective: Develop an open source toolbox that facilitates data extraction, analysis, artifact correction and standardization for the DBS research community. Background: Novel sensing enabled implantable…Parkinson’s disease symptom asymmetry at disease onset corresponds to low-beta power asymmetry in the subthalamic nucleus
Objective: Compare beta-power in the subthalamic nucleus (STN) between the most affected and least affected body side at disease onset. Background: Exaggerated beta activity (13–35…At-home prolonged adaptive deep brain stimulation improves symptoms and reduces side effects in Parkinson’s disease
Objective: Objective: To assess the effect of at-home adaptive deep brain stimulation (aDBS) on symptoms and treatment-associated side-effects in one patient with Parkinson’s disease (PD),…Personalization of deep brain stimulation using local field potentials to drive adaptive DBS: a case series
Objective: To observe chronically recorded local field potentials (LFPs) in patients receiving Deep Brain Stimulation (DBS) for Parkinson’s Disease (PD) and using an adaptive DBS…
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