Opicapone Improves Global Non-Motor Symptoms Burden in Parkinson´s Disease: An Open-label Prospective Study
Objective: The aim of this study was to analyze the effectiveness of opicapone on global non-motor symptoms (NMS) burden in Parkinson´s disease (PD). Background: Some…Blood biomarkers and their association with non-motor symptoms in early Parkinson’s Disease
Objective: To identify if baseline blood biomarkers are associated with non-motor symptoms in early PD. Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder with…Quality of life changes after subthalamic stimulation for Parkinson’s disease depend on nonmotor and motor symptoms clusters
Objective: To analyze quality of life (QoL) changes after subthalamic stimulation (STN-DBS) based on a short list of baseline nonmotor and motor symptoms in Parkinson’s…Mindfulness based program for newly diagnosed Parkinson’s patients.
Objective: To investigate the impact of 8-week course of Mindfulness based intervention program on motor and or non-motor symptoms of PD assessed by improvement in…The relationship of non-motor symptoms in Parkinson’s disease
Objective: Evaluation of non-motor symptoms in patients with Parkinson's disease, evaluation of the relationship of autonomic and neuropsychiatric disorders. Background: This work included a comprehensive…Liraglutide once daily versus placebo in Parkinson’s disease: a randomized, double-blind, placebo-controlled trial
Objective: To test safety and efficacy of the glucagon-like peptide 1 (GLP-1) agonist liraglutide in idiopathic Parkinson’s disease (PD). Background: Insulin resistance (IR) may play…Non-motor symptoms burden in motor-fluctuating patients with Parkinson’s disease may be alleviated by safinamide: the VALE-SAFI study
Objective: The present study aimed to explore the effect of safinamide treatment on NMS and quality of life in motor-fluctuating PD patients. Background: Parkinson’s disease…Basal forebrain contribution to cognitive deficits during medication “off” state in Parkinson’s disease
Objective: We sought to determine whether structural integrity of cholinergic Basal Forebrain (BF) was associated with subjective cognitive deficits experienced during medication “off” time Parkinson’s…Frequency of non-motor symptoms in GBA-PD may differ in carriers of mild vs. severe pathogenic variants
Objective: Parkinson's disease (PD) patients with pathogenic variants in the GBA (glucocerebrosidase) gene (GBA-PD) were reported to exhibit a younger age at onset, faster progression…Lateralization of cochlear dysfunction as a specific biomarker of Parkinson’s disease; role for cholinergic transmission?
Objective: To understand to what extent an early cochlear dysfunction may represent an additional non-motor signature of Parkinson’s disease (PD) patients. Further, whether it may…
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