Identifying subjects at high risk for prodromal Parkinson’s Disease using dopamine transporter imaging deficit in a step-wise recruitment strategy: Data of Healthy Brain Ageing (HeBA)
Objective: To optimize screening for subjects with dopamine transporter (DaT) imaging deficit being at high risk for prodromal Parkinson's disease (PD). Background: Efficient screening methods…Alpha-Synuclein Aggregates in the Olfactory Epithelium of Subjects with Parkinson Disease, Dementia, COVID-19, and in Aged Controls
Objective: We sought to examine whether neuroepithelial structures of the nasal cavity differ between individuals diagnosed with a Lewy body disorder vs those with COVID19…PREDIGT 2.0: A Self-Administered, Two-Step Screening Tool to Identify Individuals with Parkinson’s Disease
Objective: To pilot the 2-step PREDIGT Score model for feasibility and improve it by simplifying both steps. Background: We previously demonstrated that the original PREDIGT…16-years of Evaluations for Prodromal Parkinson Features in an At-Risk Cohort with Gaucher Disease
Objective: To evaluate prodromal features of Parkinson disease in a cohort of "at-risk" Gaucher patients and GBA1 carriers . Background: Variants in GBA1 mutations are…Olfactory-Trigeminal Interactions in Parkinson’s Disease Compared to Other Olfactory Disorders
Objective: To investigate the interaction between the olfactory and trigeminal systems in Parkinson’s disease (PD) as opposed to other forms of olfactory dysfunction and controls…Utility of Digital Olfactory Assessment (Sensify) in Parkinson’s Disease: Preliminary Findings from the IPDGC Africa in Egypt
Objective: Validate a digital olfactory assessment for Parkinson’s disease (PD) in Egyptian participants by comparing olfactory performance in PD patients, healthy controls, and those with…Integrating Non-Motor Symptoms and Gender Variability in Machine Learning for Early Parkinson’s Disease Detection
Objective: Our study aimed to develop a machine learning (ML) model for the early detection of Parkinson's disease (PD), utilizing non-motor symptoms (NMS) and DNA…Odor-specific symptoms in Parkinson’s disease – UPSIT odor identification status versus clinical severity.
Objective: To explore correlations between the identification status of individual odors in the Pennsylvania Smell Identification Test (UPSIT) and the clinical severity of Parkinson’s disease…Parkinson’s disease biomarkers in human olfactory cleft mucus
Objective: To investigate and identify biomarkers for PD from human olfactory cleft mucus Background: Olfactory loss is an early symptom of PD, often preceding motor…Association between Non-Motor Parkinson’s disease symptoms and hyposmia in a population-based cohort
Objective: To describe the association between different Parkinson’s disease (PD) related non-motor symptoms (NMS) and hyposmia in a population-based cohort. Background: Olfactory dysfunction is of…
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