Surface mechanised nano-formulation of naringenin as adenosine A2A receptor antagonist against in Neurological associated problem of Parkinson
Objective: In the current experimental study, we intended to develop Surface mechanized nano-formulation of naringenin (NG) as potent A(2A)AR antagonists against parkinson’s disease. Background: One…Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial
Objective: To investigate whether women and men with Parkinson's disease (PD) may differ in their biochemical and clinical responses to long-term treatment with urate-elevating inosine.…Curcumin improves cognitive function in rotenone-induced rat model of Parkinson’s disease (PD)
Objective: In this study, we aimed to investigate the neuroprotective effect of curcumin against rotenone-induced memory impairments in rat PD model. Background: In PD, oxidative…Resistance to Parkinson’s disease among LRRK2 mutation carriers is associated with higher plasma levels of urate but not its purine precursors
Objective: To determine whether plasma purine concentrations differ between people with Parkinson's disease (PD) and matched controls among carriers of pathogenic mutations in Leucine-Rich Repeat…MANF improves the MPP+/MPTP-induced Parkinson’s disease via improvement of mitochondrial function and inhibition of oxidative stress
Objective: This study aimed to investigate the therapeutic effect of mesencephalic astrocyte-derived neurotrophic factor (MANF) on the MPTP/MPP+-induced model of Parkinson's disease (PD) and the…Freezing of Gait in Parkinson’s Disease: Clinico-biochemical Observations
Objective: We aimed to compare motor and non-motor functions, 2D-spatiotemporal gait parameters and serum oxidative markers including catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA)…Protective effects of Mucuna pruriens seed on rat brain: A therapeutic potential drug for Parkinson’s disease
Objective: Objective of present study was evaluate neuroprotective and antiparkinson effects of Mp seed extract on Parkinsons brain of rats. Background: Parkinson’s disease (PD) is…Effects of Glial Heme Oxygenase-1 on Neuronal Alpha-Synuclein in the GFAP.HMOX1 Mouse Model of Parkinson’s Disease
Objective: To determine whether astroglial HO-1 transduces environmental and endogenous stressors into patterns of neural damage which promote the toxicity of neuronal alpha-synuclein. Background: The…Analysis of serum non-mercaptoalbumin in patients with Parkinson’s disease
Objective: It is well known that the oxidative stress might be associated with the pathomechanisms of Parkinson’s disease (PD). In this study, we assessed serum…Increased bilirubin levels in Parkinson’s disease from southern Spain.
Objective: To evaluate serum bilirubin concentration in Parkinson’s disease (PD) compared to healthy controls (HC) and to investigate its associations with motor and non-motor features…
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