Movement Disorders as an Atypical Presentation of Alzheimer’s Disease: A Cerebrospinal Fluid Biomarker-Based Study
Objective: To identify patients with atypical presentations of Alzheimer’s disease (AD) associated with movement disorders and to characterize their clinical features and CSF biomarker profiles…Neuropsychiatric Symptom Changes in Parkinson’s Disease Patients Treated with Different Doses of Donepezil: A 24-Week Follow-up Study
Objective: This study analyzed the effectiveness of donepezil therapy on neuropsychiatric symptoms in Parkinson’s disease with cognitive impairment (PD-CI), depending on the dose administered. Background:…Amyloid Burden in the Precuneus and Posterior Cingulate Gyrus Is Associated With Cognitive Function and White Matter Microstructure in Lewy Body Dementia
Objective: To investigate the relationship between amyloid burden measured by PET and white matter microstructural alterations assessed by advanced diffusion MRI in individuals with Parkinson’s…The Burden of Cognitive Impairment in People with Parkinson’s across Outpatients and Prevalent Patients in Coastal Kenya: A Transforming Parkinson’s Care in Africa (TraPCAf) Study
Objective: To describe the rate and severity of cognitive impairment within the coastal Kenyan cohort of TraPCAf. Background: Cognitive impairment is a well-recognised non-motor symptom of PD, however there is very…A Switching from Oral Donepezil to a Twice-Weekly Korean Transdermal Donepezil Patch in Patients with Dementia with PD
Objective: Aimed to assess caregivers’ satisfaction with and preference for a transdermal donepezil patch compared with conventional oral formulations in patients with d-PD, with the…Unveiling a rare case: Novel TBK1 variant presenting as Multiple system atrophy-like phenotype
Objective: Tumour necrosis factor NF-ƘB activator (TANK) binding kinase 1 (TBK1) is necessary for immune and inflammatory responses. Reports of TBK1 with neurodegeneration are noted…Impaired glymphatic clearance independently contributes to poor outcomes in Parkinson’s disease
Objective: Clarify how glymphatic clearance impacts cognition in PD and its interaction with established imaging markers. Background: Impaired glymphatic clearance may contribute to pathological accumulations…Prevalence and Clinical Characteristics of Parkinson’s disease in Rural Nepal: A Community-Based Cross-Sectional Study
Objective: This study aims to determine the prevalence of PD in rural Nepal and characterize its clinical features in an effort to bridge the gap…Patients’ Perspective on Screening for Non-Motor Symptoms in Parkinson’s Disease, A QI Project
Objective: To assess deficiencies in patient care for individuals with Parkinson's disease in neurology clinics, with a particular focus on nonmotor symptoms. Background: While motor…Beyond Motor Symptoms: The Interplay Between Non-Motor Symptoms and Caregiver Challenges in Late-Stage Parkinson’s Disease
Objective: To assess the relationship of non-motor (neuropsychiatric (NPS)) symptoms with the severity of motor symptoms of Parkinson’s Disease (PD). And to study the impact…
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