Video-to-Home Cognitive-Behavioral Therapy for Veterans with Depression and Parkinson’s Disease: A Randomized Controlled Trial
Objective: For the nearly 100,000 veterans with Parkinson’s disease (PD) receiving Veterans Affairs (VA) health care, depression is prevalent, yet often undiagnosed or undertreated. This…Effects of multimodal balance training supported by rhythmical auditory stimuli in people with advanced stages of Parkinson’s disease: A randomized clinical trial
Objective: To study the effectiveness of balance training with and without rhythmical auditory cues in people with advanced stages of PD (H&Y4). Background: Non-pharmacological interventions…Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease: ADAPT-PD Trial: A Prospective Single-Blind, Randomized Crossover, Multi-Center Trial of Deep Brain Stimulation Adaptive Algorithms in Subjects with Parkinson’s Disease
Objective: To demonstrate safety and effectiveness of adaptive deep brain stimulation (aDBS) algorithms in subjects with Parkinson’s disease (PD). Background: DBS is an effective therapy…Oral Venglustat in Parkinson’s Disease Patients With a GBA Mutation: Study Design of Part 2 of the MOVES-PD Trial and Patient Characteristics
Objective: Describe the study design of Part 2 of the MOVES-PD trial (NCT02906020), and report patient characteristics. Background: Mutations in the glucocerebrosidase (GBA) gene are…Prevalence and Characteristics of Postural Deformities in Thai Patients with Parkinson’s Disease
Objective: We aimed to investigate the prevalence, clinical characteristics and quality of life (QoL) in Thai Parkinson's disease (PD) patients with postural deformities (PostD) and…Motor subtype change between OFF and ON periods in patients with Parkinson’s disease
Objective: To identify if there is any difference in the motor subtype of PwPD between "off" stage and "on" stage. Background: Patients with Parkinson’s disease…New compound increasing glucocerebrosidase activity on primary cell cultures obtained from patients with GBA-associated Parkinson’s disease
Objective: To determine whether new chemical modifications of the previously described allosteric GCase chaperone N607 (Aflaki E et.al Neurosc. 2016) increase GCase activity in monocyte-derived…Disease stage and UMSARS progression: Implications for clinical trials
Objective: To study the rate of progression of multiple system atrophy (MSA) and assess for a potential ceiling effect of the Unified Multiple System Atrophy…Development and validation of a profile of peripheral immune biomarkers for Parkinson’s disease: A multicenter, retrospective study
Objective: This multicenter study was designed to investigate the association between multiple peripheral immune biomarkers and the risk of Parkinson’s disease (PD). Background: Several studies…Does “5-2-1” identify patients with suspected Advanced Parkinson’s Disease? Evidence of clinical accuracy from G7 countries
Objective: Evaluate the psychometric properties of (i) the “5-2-1” criteria and (ii) consensus-driven clinical indicators of suspected advanced Parkinson’s disease (APD). Background: Recent consensus panel…
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