Bilateral Putaminal AAV2-GDNF Delivery the Treatment of Advanced Parkinson’s Disease
Objective: To investigate the safety, tolerability, and early clinical efficacy of escalating doses of AAV2-GDNF delivered into the bilateral putamen of patients with advanced PD…What patients need – a qualitative analysis of consultations prior to deep brain stimulation in patients with Parkinson’s disease
Objective: To evaluate the different needs of patients with Parkinson’s disease (PD) prior to deep brain stimulation (DBS). Background: DBS is a well established and…A Smart Device System (Wearable technology band) to Identify New Phenotypical Characteristics in Parkinson‘s disease patients
Objective: To develop methods for analyzes and monitor of gait data via smart device system and identify new phenotypical characteristics in PD patients. Background: Parkinson's…Complex Training of Balance in Parkinson’s Disease
Objective: To study the effect of biofeedback (BFB) and balance training in patients with Parkinson disease (PD). Background: Gait and balance disorders, characterized by freezing…A review of interactive voice response systems in Parkinson’s Disease
Objective: The objective of this literature revision is to review and analyze the current research on the uses of Interactive Voice Response Systems (IVRS) in…Does information from the Personal KinetiGraph™ (PKG) influence neurologists´ treatment decisions?
Objective: To evaluate if PKG data influences neurologists´ treatment decisions in routine clinical care of patients with Parkinson´s disease. Background: The PKG movement recording system is…Transcranial ultrasound in atypical parkinsonism: how reliable is it in real clinical practice? A multi-centre comprehensive study
Objective: To assess real clinical practice usefulness of transcranial ultrasound in atypical parkinsonism differential diagnosis, and to perform a critical analysis of previous literature in…Cholecalciferol (VD3) attenuated motor deficits and dyskinesia in Hemi-Parkinsonian mice: behavioural, biochemical & electrophysiological implications
Objective: The study investigated the impacts of VD3 on behavioural indices, dopamine metabolism, DA transport, BDNF, corticostriatal neural activities and the possible mechanism of action…Safety and Tolerability of opicapone in Parkinson’s disease
Objective: To evaluate safety and tolerability of opicapone as an add‐on treatment to levodopa in Parkinson's disease (PD) patients. Background: Opicapone is a recently approved…Role of microRNA-153 and -223 in Parkinson disease
Objective: To assess the therapeutic and diagnostic potential of microRNA (miR)-153 and miR-223 in mice and humans with parkinsonism. Background: Dysregulated miRNAs play a major…
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