Neurological Wilson’s disease: another form of tauopathies?
Objective: The authors would hope to identify distribution of Tau protein within the brain of Wilson's disease patients by tau-targeted positron emission tomography (PET) tracers Background:…Nutritional Assessment in X-linked Dystonia Parkinsonism: Preliminary Results from a Pilot Study
Objective: This pilot study aims to evaluate the nutritional status of XDP patients using anthropometric measurements and nutritional assessment tools, and to determine the prevalence…Assessment of Postural abnormalities in Early-stage Parkinson’s Disease Using a Posture Analyzing and Virtual Reconstruction Device
Objective: To investigate whether an RGB camera-based system with AI-driven analysis, the posture-analyzing and virtual reconstructing system (PAViR), can effectively assess postural abnormalities in early-stage…Gut Microbiome Metagenomics in Parkinson’s Disease Stratified by the Asian-Prevalent LRRK2 Variants p.G2385R and p.R1628P
Objective: To compare gut microbiome profiles of manifesting LRRK2 p.G2385R or p.R1628P carriers (LRRK2-PD) and idiopathic Parkinson’s disease patients (iPD). Background: Leucine-rich repeat kinase 2…Investigating the Role of Biallelic EPG5 Variants in Parkinson’s Disease
Objective: Investigate EPG5 role in PD aetiology. Background: Disruption of the lysosome-autophagy pathway is a recurrent feature in Parkinson’s disease (PD). EPG5 bi-allelic loss-of-function variants have been…Comparison of Motor Severity in Individuals with Drug-Induced Parkinsonism and Idiopathic Parkinson’s Disease A Systematic Review and Meta-Analysis
Objective: To compare motor severity between individuals with drug-induced Parkinsonism (DIP) and idiopathic Parkinson’s disease (iPD) Background: DIP and iPD may present with similar motor…Corticobasal Syndrome: A Single-Center Retrospective Review
Objective: To characterize the demographic, clinical and diagnostic features of patients diagnosed with corticobasal syndrome (CBS) seen at The Queen’s Medical Center in Honolulu, Hawaii.…Fracture Burden and Health-Related Quality of Life in Older Adults with Parkinson’s Disease in Rural India: A Community-Based Study
Objective: This study aimed to examine the relationship between fracture history and health-related quality of life (HRQoL) among elderly individuals with Parkinson’s disease residing in…Novel Modeling Approach for Comparing Treatment-Naive and Post-Treatment Neuronal Synucleinopathy Progression Using Multi-Modal PPMI Data
Objective: To characterize multi-domain progression over the course of Neuronal alpha-Synuclein Disease (NSD), in both treatment-naive and treated individuals. Background: Neuronal alpha-Synuclein Disease (NSD), a…Diagnostic Delay in Multiple System Atrophy: Sociodemographic and Clinical Predictors in a Single-Center Cohort
Objective: To evaluate sociodemographic and clinical predictors of diagnostic delay in multiple system atrophy (MSA) at a single tertiary referral center. Background: MSA is a…
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