Dopamine-Responsive Post-Anoxic Parkinsonism
Objective: To describe a retrospective case series of five cases of dopamine-responsive post-anoxic parkinsonism. Background: Parkinsonism following hypoxic ischemic damage of the basal ganglia is…Diagnostic mismatches between clinical assessment, imaging and alpha-synuclein biomarkers in parkinsonian syndromes
Objective: To analyze the frequency of matching information provided by traditional clinical assessment, dopamine transporter (DaTscan), and skin biopsy results in patients with undiagnosed parkinsonian syndromes. Background:…The Genetic and Phenotypic Spectrum of Primary Familial Brain Calcification in a large cohort from China
Objective: To update the genetic spectrum of primary familial brain calcification (PFBC) and phenotypic characteristics in genetically diagnosed PFBC, and provide genotype-imaging-symptoms correlations of PFBC.…Oxidative stress in Progressive Supranuclear Palsy
Objective: The goal of the study is to evaluate the significance of oxidative stress in the examination and pathophysiology of Progressive Supranuclear Palsy (PSP). Additionally,…Yes, Palliative Care in Advanced Parkinsonism pays off: a pilot Cost-effectiveness Analysis
Objective: To evaluate the cost-effectiveness of a specialized multidisciplinary team approach (ACT-PD) compared to standard care (SC) in those living with advanced parkinsonian syndromes (APS),…The Effect of Melatonin on Sleep Quality and Daytime Sleepiness in Parkinson’s Disease: A Systematic Review and Meta-analysis of Randomized Placebo-Controlled Trials
Objective: This study aims to systematically quantify the impact of melatonin on sleep quality and daytime sleepiness in individuals diagnosed with Parkinson’s disease (PD). Background:…Catalan MSA Registry (CMSAR): Applying new Clinical Criteria and Biomarkers for Increasing Diagnostic Accuracy, is New Better?
Objective: To reassess the CMSAR and determine if new criteria and new biomarkers can enhance diagnostic accuracy. Background: The CMSAR, conducted between 2015 and 2019,…Accuracy of Clinical features for Substantia Nigra Hypopigmentation and Cortical Lewy Body Presence in the Oldest-Old: The 90+ Study
Objective: To improve clinical diagnostic accuracy of Lewy Body Dementia (LBD), we assessed if frontal release signs are a useful screening tool for cortical Lewy…Mixed Brain Pathology in Neurodegenerative Parkinsonism and Dementia
Objective: To assess the presence of mixed neurodegenerative pathology and its proportion in the prospective cohort of patients treated for any phenotype of neurodegenerative parkinsonism,…Cognitive Side Effects to Initial Levodopa Exposure as a “Red Flag”: A Retrospective Study
Objective: To assess if presence of cognitive side effects during an initial levodopa trial suggests the ultimate diagnosis of atypical Parkinson (APD) vs Parkinson disease…
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