Functional connectome in Parkinson’s disease mild cognitive impairment
Objective: To unravel functional connectivity (FC) traits in Parkinson’s disease mild cognitive impairment (PD-MCI). Background: PD-MCI is a well-known risk factor for PD associated dementia.…Frequency-dependent abnormalities of intrinsic brain activity in Parkinson´s disease
Objective: The study objective was to assess the changes in amplitude of low frequency fluctuations (ALFF) in patients with Parkinson´s disease (PD) as compared to…Mitochondrial Complex 1, Sigma 1 Receptor and Synaptic Vesicle protein 2A density in early de novo patients with Parkinson’s Disease: pilot PET data
Objective: In this study, we evaluated the density of Mitochondrial complex 1 (MC1), sigma 1 receptor (s1R) and Synaptic Vesicle protein 2A (SV2A) in early…The role of Synaptic vesicle protein 2A (SV2A) in patients with Parkinson’s disease dementia and Dementia with Lewy bodies: An in vivo [11C]UCB-J PET study
Objective: We aimed to investigate the role of synaptic vesicle glycoprotein 2A (SV2A) in Parkinson’s disease dementia (PDD) and Dementia with Lewy bodies (DLB) using…Blue light therapy glasses in Parkinson’s disease: patients’ experience and effectiveness
Objective: We aimed to assess how patients experience the use of blue light glasses, a novel way of delivering light therapy, aiming to optimise compliance…Unilateral leg tremor on sitting crossed-legged position as the initial manifestation of Parkinson’s disease
Objective: Our aim is to report an unusual case of initial manifestation of Parkinson's disease, which showed unilateral leg tremor on sitting crossed-legged position on…Efficacy and safety of zonisamide in patients with dementia with Lewy bodies with parkinsonism: pooled analysis of phase 2 and 3 trials
Objective: To characterize the efficacy and safety of zonisamide (ZNS) in patients with dementia with Lewy bodies (DLB) with parkinsonism, a pooled analysis of two…Biphasic Dyskinesias in Parkinson’s disease Patients treated with Levodopa/Carbidopa Intestinal Gel: Insights from a Multicenter Retrospective Analysis
Objective: We aimed to characterize Parkinson's disease (PD) patients who developed the onset of new troublesome dyskinesias after Levodopa-Carbidopa Intestinal Gel (LCIG) initiation. We were…Parkinson’s disease and intermittent hypoxia training: beneficial or harmful?
Objective: To systematically review the scientific evidence for beneficial or harmful effects of intermittent hypoxia that were used in Parkinson’s disease (PD) in clinical and…Effects of safinamide and rasagiline on in vivo glutamate release in 6-OHDA hemilesioned rats
Objective: To investigate the effects of safinamide (saf) and rasagiline on in vivo glutamate (Glu) release in the 6-hydroxydopamine (6-OHDA) hemilesioned rat model of Parkinson’s…
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