Molecular mechanisms of GCH1-associated Parkinson’s disease
Objective: To unravel the molecular mechanisms by which loss of GCH1 function enhances the risk of Parkinson´s disease (PD). Background: Loss-of-function mutations in GCH1 are…Contribution of individual motor signs to striatal dopamine deficiency in parkinsonism
Objective: The primary aim of the study was to investigate if any individual motor sign could be used clinically to predict striatal dopamine deficiency. Secondary…Characteristics of brain mri in patient with Parkinson’s disease
Objective: To investigate the characteristics and brain MRI findings in patient with Parkinson’s Disease Background: Parkinson's Disease is a chronic, progressive neurodegenerative disease that is…Evaluation of bradykinesia in Parkinson’s disease using a computerised evolutionary algorithm
Objective: Application of a computerised algorithm to kinematic motor recordings to distinguish parkinsonian bradykinesia from normal movement. Background: Bradykinesia, the only obligatory physical sign for…Sexual Dysfunction in Women with Parkinson’s Disease
Objective: To assess the prevalence and severity of sexual dysfunction (SD) in women with Parkinson’s Disease (PD) in comparison to general population (GP), highlight the…Pain is correlated with other motor and non-motor symptom in Parkinson’s disease
Objective: Study pain occurrence and appearance in Parkinson’s disease (PD), and its relationship with other motor and non-motor symptoms like constipation and footsteps. Background: The…Validation of the French version of the Munich Dysphagia Test-Parkinson’s disease (MDT-PD) in a multilingual population of the Luxembourg Parkinson’s Study (HELP-PD)
Objective: To provide the psychometric validation of the French MDT-PD in the Luxembourgish multilingual population. Background: The MDT-PD, developed and validated in German [1], is…Stigma and communication in people with Parkinson’s disease (PPD)
Objective: To present results about stigma in PPD from a Parkinson’s Workshop. These are preliminary results in the path to address the main project question…B lymphocytes may be protective in early Parkinson’s disease and in an animal model of dopaminergic cell death
Objective: To investigate B lymphocyte phenotype and function in human PD and in an animal model of disease. Background: The clinical course in Parkinson’s disease…Red cell distribution with levels in Parkinson’s disease patients
Objective: Parkinson’s Disease is a neurodegenerative disorder caused by oxidative stress, protein changes and mitochondrial disfunction. Lately, it has been suggested that inflammatory cytokine levels…
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