Expanding Diversity of Parkinson’s Disease and Related Disorders Genetic Data: from the Global Parkinson’s Genetics Program
Objective: To expand the research dataset for Parkinson’s Disease (PD) and related disorders by including >50,000 participants globally who have been genotyped or whole genome…Characteristics of tremor frequency oscillatory neurons in the basal ganglia and thalamus in Parkinson’s tremor
Objective: To characterize tremor frequency oscillatory neurons in the basal ganglia and thalamus in patients with Parkinson’s tremor. Background: Evidence that the basal ganglia and…Movement Disorders in Autoimmune Encephalitis: A case series of 11 cases.
Objective: Describe abnormal movements associated with autoimmune encephalopathies (AIE) Background: Movement disorders are a hallmark feature of autoimmune encephalitis (AIE), playing a pivotal role in…Diagnostic Spectrum in a Cohort of Atypical Atypical Parkinsonism
Objective: To retrospectively look at atypical Parkinsonism mimics in our cohort and reappraise the clinical features of these subset of patients Background: Atypical parkinsonism syndromes…Quantitative Assessment of X-linked Dystonia-Parkinsonism Using Wearable Sensing Technology
Objective: To create a quantitative, objective framework for assessing combined dystonia parkinsonism using kinematic data from wearable sensors combined with machine learning (ML), enabling clinician-independent…Impact of Striatal Degeneration on Clinical Phenotype in Idiopathic Normal Pressure Hydrocephalus: A Comparative Analysis
Objective: To compare the clinical phenotype between patients with normal and abnormal dopamine transporter scan (DaTscan) in probable and definite idiopathic normal pressure hydrocephalus (iNPH).…Managing Cognitive Decline in Vascular Dementia with Associated Parkinsonism
Objective: The intersection of vascular dementia (VaD) and secondary parkinsonism presents a complex therapeutic conundrum, particularly in geriatric populations. This study aims to elucidate the…Abstract: Trends in Movement Disorders related death in the United States from 1999 to 2020
Objective: We aimed to analyze the mortality and prevalence of movement disorders in the United States from 1999 to 2020 to compare disparities among various…Effects of ectopic dopamine D2 autoregulation of raphe-striatal projecting neurons on established L-DOPA-mediated behaviors in a hemiparkinsonian rat model
Objective: Levodopa (LD) is the standard treatment for Parkinson’s Disease (PD) despite risk of LD-induced dyskinesia (LID) development within a decade of treatment. Serotonergic (5-HT)…Automated Imaging Differentiation of Parkinsonism (AIDP): A Prospective 21-site Trial within the Parkinson’s Study Group
Objective: To prospectively test the performance of Automated Imaging Differentiation of Parkinsonism (AIDP), a machine learning based diagnostic biomarker software for Parkinson’s disease (PD), multiple system atrophy Parkinsonian…
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