Efficacy of incobotulinumtoxinA in patients with sialorrhea, as assessed using the modified Radboud Oral Motor Inventory for Parkinson’s disease (mROMP): Results of the SIAXI study
Objective: The pivotal double-blind, randomised Phase III SIAXI study (NCT02091739), assessed the efficacy and safety of incobotulinumtoxinA 75 or 100 U for sialorrhea. Co-primary endpoints…Early stage Parkinson’s disease phenotypes
Objective: Identify Parkinson’s disease (PD) subpopulation clusters present at disease onset using a number of motor and non-motor phenotypes. Background: PD is considered a syndrome,…Is Heart Rate variability a differential biomarker in REM sleep behavior disorder, Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy?
Objective: Heart rate deceleration capacity (DC) and heart rate variability index (HRVI) as potential biomarkers for autonomic dysregulation were studied in subjects (each group N=10)…Dopaminergic dysfunction and abnormal metabolic network activity in REM sleep behavior disorder
Objective: This study is to investigate the correlations between the abnormalities in the distribution of striatal dopamine transporter (DAT) and the expression of Parkinson's disease…Unveiling the function of altered gut microbiota composition in Parkinson’s disease
Objective: To investigate the gut microbiome and metabolome in Parkinson’s disease (PD). Background: Recent evidence revealed that gut microbes promote alpha-synuclein pathology and motor deficits…Bone health and laboratorial correlations of Vitamin D in Parkinson’s disease
Objective: To evaluate the correlation between levels of 25 (OH)D (Vitamin D) and Bone Mineral Density (BMD) in a parkinsonian population. Background: Considering a limiting…Direction of Turning in Parkinson’s Disease: More Affected Side or Less Affected Side?
Objective: The aim of this study is to investigate differences of gait characteristics according to direction of turning more and less affected side (MAS and…Brain Perfusion pattern linked to depressive state in Parkinson’s: An arterial spin labelling MRI study
Objective: To investigate patterns of cerebral blood flow alteration associated with depressive state in Parkinson’s disease (PD) by using principal component analysis of arterial spin…Single limb stance test performance – Difference between tremor dominant and akinetic rigid dominant parkinson’s disease – A pilot study
Objective: The objective of the study is to compare single-limb stance test performance between tremor dominant (TD) and akinetic rigid dominant (ARD) Parkinson's disease patients.…Knowledge of Parkinson’s Disease in Urban Population of Kyrgyz Republic
Objective: To assess public knowledge of Parkinson's disease (PD) in an urban population in Kyrgyz Republic. Background: Poor awareness and knowledge regarding PD among the…
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