Putative treatment of Parkinson’s Disease using extract of Bacopa monnieri
Objective: Bacopa monnieri is largely treasured as a revitalizing herb used by Ayurvedic medical practitioners for almost 3000 years. The herb has been mentioned in…Safety and Efficacy of Levodopa-Carbidopa Monotherapy in Patients with Advanced Parkinson’s Disease
Objective: Evaluate efficacy/safety of levodopa-carbidopa intestinal gel (LCIG) daytime monotherapy (with/without nighttime oral carbidopa/levodopa) vs polytherapy (LCIG with >1 adjunctive therapy) in advanced Parkinson’s disease…A randomized double-blind placebo-controlled trial of probiotics for constipation in Parkinson’s disease
Objective: To investigate the effects of probiotics on constipation in PD, using a randomized controlled trial (RCT) design Background: Non-motor symptoms (NMS) cause significant disability…An early-onset parkinsonism revealing a Gaucher disease with a heterozygous mutation in GBA gene: A case report
Objective: To report a case of a late-onset Gaucher disease (GD) revealed by an atypical Parkinson disease. Background: GD is an autosomal recessive lysosomal disorder,…8-Contact Multiple Independent Current Control vs. 4-Contact Standard Deep Brain Stimulation of Subthalamus in Parkinson’s disease: a Double-blind Cross-over Trial
Objective: To explore the hypothesis that flexible stimulation (multiple independent current control over 8 contacts/hemisphere) is superior to standard stimulation (standard stimulation over 4 contacts)…Characterizing Bulbar Dysfunction in X-Linked Dystonia-Parkinsonism (XDP): A Pilot Study
Objective: This study aims to characterize bulbar motor impairments in patients with X-linked XDP and to identify clinical correlates for prediction of aspiration. Background: X-linked…Submandibular gland is a suitable tissue for alpha synuclein pathology in Parkinson’s disease
Objective: To validate the role of α-synuclein (AS) pathology in submandibular gland (SMG) as a biomarker for Parkinson disease (PD). Background: The pathologic hallmark of…Effectiveness and costs of specialised physiotherapy given via ParkinsonNet: A retrospective analysis of medical claims data
Objective: To study the long-term benefits of specialised physiotherapy using the ParkinsonNet approach in real-world practice. Background: Trials show that specialised allied health interventions are…Palliative Virtual Home Visits for Atypical Parkinsonian Disorders (PVH-Park Study)
Objective: To determine the feasibility and preliminary efficacy of implementing multidisciplinary "palliative virtual home" (PVH) visits for caregivers (CGs) & patients with Atypical Parkinsonian Disorders…Progressive Supranuclear Palsy and Eye of the Tiger Sign
Objective: To report a typical progressive supranuclear palsy case with "eye of the tiger sign" on MRI Background: Progressive supranuclear palsy (PSP); is a degenerative…
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