Combined Motor and Cognitive Training Improves Motor and Cognitive Function in People with Parkinson’s Disease and Freezing of Gait
Objective: Investigate whether combined motor and cognitive training improves motor and cognitive function in people with PD and freezing of gait (FOG). Background: FOG affects…Myoclonus in the Elderly: Retrospective Analysis of Clinical and Electrophysiological characteristics of patients referred to an electrophysiology laboratory
Objective: In this report, we aimed to investigate clinical and electrophysiological features of patients with late-onset myoclonus. Background: Myoclonus is characterized by sudden, brief and…Effects of dopaminergic medication on executive function in Parkinson’s disease differs according to the clinical stage
Objective: We examined the effect of dopaminergic medication on executive function in 24 drug-naïve PD patients (de novo group) and in 21 PD patients on…Decision making under uncertainty in medicated and un-medicated Parkinson’s disesase
Objective: To evaluate decision making under risk in Parkinson’s disease patients, both medicated and un-medicated states probing constituent cognitive operations driving choice. Background: Prior literature…eEF1A2 promotes cell survival and protects against MPP+-induced apoptotic neuronal death through the PI3K/Akt/mTOR pathway
Objective: To assess the correlation of eEF1A2 and PI3K/Akt/mTOR expression and investigate the pro-survival role of eEF1A2 in NG108-15 rodent neuroglioma cells. Background: Eukaryotic protein…A member of the HSP40/DNAJ family is a novel gene for early-onset parkinsonism
Objective: We aim to implicate novel genes/mutations using whole-exome sequencing (WES) in selected pedigrees. Background: Mutations have been identified in only 30% of familial parkinsonism.…Electrophysiological markers for emotional and cognitive impairment in Parkinson’s disease
Objective: This study aims to identify markers for emotional and cognitive dysfunctions in Parkinson’s disease (PD) using non-invasive electroencephalography (EEG). This study investigates event related…What strategies do Parkinson’s disease patients use for getting out of bed in the early morning? Preliminary results from home video analysis of 22 patients.
Objective: To classify PD patients’ getting out of bed strategies using home video analysis. Background: Getting out of bed represents a major difficulty of early…Validation of the MDS Research Criteria for Prodromal Parkinson’s Disease: longitudinal assessment in a REM sleep behavior disorder (RBD) cohort
Objective: 1) To calculate diagnostic accuracy of the Movement Disorder Society (MDS) prodromal criteria to predict conversion to Parkinson’s disease (PD) or dementia with Lewy…End of Life Care in Parkinson’s Disease
Objective: We aim to identify the current practice at the Royal Devon & Exeter NHS trust of managing Patients with PD at the end of…
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