Interaction of dietary protein with levodopa in Parkinson disease.
Objective: To study the effect of dietary protein on levodopa effectiveness in Parkinson disease (PD) patients. Background: Levodopa transport across the blood brain barrier is…MRI-based Brain Networks of Perfusion and Structural Abnormalities in Patients with Cerebellar Variant of Multiple System Atrophy
Objective: To identify MRI-based brain networks of cerebral perfusion and structural abnormalities in cerebellar variant of MSA. Background: MSA consists clinically of parkinsonian (MSA-P) and cerebellar (MSA-C) variants. Previous FDG PET studies have…Ghrelin and the IGF-1 axis in cognitive impairment in PD
Objective: To explore the association of acyl-ghrelin (AG) levels with cognitive impairment (CI) in PD Background: Unintended weight loss (UWL) in PD is associated with…TMEM230 mutation analysis in Parkinson’s disease in a Chinese population
Objective: To investigate the prevalence of TMEM230 mutations in Chinese patients with familial and sporadic PD. Background: Recently, Hanxiang Deng and colleagues identified a missense…Alteration of early endosomal trafficking causes neurodegeneration in PARK20
Objective: To elucidate the molecular basis of the Park20 by evaluating the role of synaptojanin 1 in intracellular trafficking. Background: Recently a new form of…Early-Onset Parkinson Disease with Hypocalcemia: Adult Presentation of 22q11.2 Deletion Syndrome
Objective: Report a case of early-onset Parkinson Disease with hypocalcemia and mild dysmorphic features leading to diagnosis of 22q11.2 deletion syndrome Background: The 22q11.2 Deletion Syndrome is…Predictive Ability of Clinical Timed Tests for Postural Instability and Gait Difficulty in Parkinson’s Disease
Objective: To identify clinical determinants for postural instability and gait difficulty in persons with Parkinson's disease (PD). Background: Gait deficits and postural instability in persons…Can glabellar and palmomental reflexes differentiate neurodegenerative from non-neurodegenerative parkinsonism?
Objective: To evaluate if the presence of glabellar and palmomental reflexes in patients with parkinsonism is significantly more common in neurodegenerative etiology compared with non-neurodegenerative…Pregnancy and Parkinson’s disease: A review and update
Objective: To investigate the literature on pregnancy in the setting of Parkinson’s disease (PD) in order to better understand and treat women who become pregnant.…Incorporating Specialist Independent Prescribing Pharmacist (SIPP) sessions into the Movement Disorder Service
Objective: To describe the incorporation of a prescribing pharmacist into a Multi-disciplinary Parkinson's clinic based in a University Hospital Background: Evidence shows that a multidisciplinary…
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