Fundamental limit of the alpha-synuclein immunohistochemistry using the endoscopic biopsy from the gastrointestinal tract as a biomarker for Parkinson disease: a case-control study
Objective: To investigate significance of the Lewy pathology in biopsy and surgical specimen in the gastrointestinal (GI) tract as an in-vivo biomarker for Parkinson disease (PD). Background: Alpha-synuclein…Beneficial and Protective Effects of Withania Someniferais On Mice Brain: A Therapeutic Potential Drug for Parkinson’s Disease
Objective: Objective of our study was evaluate effect of Withania Someniferais leaves on Parkinsons brain of mice Background: Parkinson’s disease (PD), an age-related disorder, is…Effects of different intensity exercises on motor function of PD rats as well as the regulation of DA
Objective: This paper research the intervention effect of the different intensity treadmill exercise on motor function of Parkinson 's diseases (PD) model rats，and explore the…Evaluating wearable sensors for objective measurement of motor features in Parkinson disease and Huntington disease – a pilot study
Objective: Evaluate the feasibility of wearable sensors in measuring motor features of individuals with PD, HD, prodromal HD, and controls in clinic and at home.…More effective rTMS site for the freezing of gait in Parkinson’s disease
Objective: The aim of study is to find brain stimulation areas showing more effective response. Background: Freezing of gait (FOG) is frustrating problem in Parkinson’s…RBD predicts the cognitive impairment in Parkinson’s disease
Objective: To assess the relationship between the presence of Rapid eye movement sleep and behavior disorders RBD and the cognitive decline of non-demented patients with PD in…Validation of a performance-based assessment of functional ability related to cognition in Parkinson’s disease
Objective: Validate the University of California San Diego Performance-Based Skills Assessment (UPSA) in Parkinson's disease (PD) Background: Diagnostic criteria for PD dementia (PDD) require significant…Apolipoprotein E ε4 allele frequency in Korean Patients with Parkinson’s disease Dementia
Objective: The Apo E allele frequencies were evaluated in Korean patients with probable PDD diagnosed by the MDS task force criteria for the diagnosis of…A neuronal model of PARK20 (SYNJ1 mutation) using patient derived iPSCs
Objective: The SYNJ1 homozygous mutation (p.Arg258Gln) leads to juvenile Parkinsonism (PARK20). SYNJ1 plays an important role in synaptic vesicle cycling, and regulating autophagic flux. We…Genetic and pharmacological rescue of DJ-1 loss-of-function caused by a c.192G>C mutation in PARK7
Objective: In this study we investigate the cellular mechanism underlying the Parkinson’s disease (PD)-associated mutation c.192G>C in PARK7 and present a compound treatment that rescues…
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