Exome sequencing in patients with impulse control disorders in Parkinson’s disease: a pilot study
Objective: To identify genetic variants associated with impulse control disorders (ICD) in Parkinson’s disease (PD) Background: ICD is frequently associated with dopamine agonist (DA) therapy…Predictors of onset of psychosis in Parkinson’s disease: “Who gets it early?”
Objective: To explore the factors which may predict the onset of psychosis in Parkinson’s disease (PD). Background: Non-motor symptoms (NMS) are commonly observed in PD.…Which self-report motor experiences of daily living best predict objective motor function in patients with Parkinson’s disease?
Objective: To identify the most important self-reported motor experience predictors of objective measures of motor impairment in patients with Parkinson's disease (PD). Background: The MDS-UPDRS has…Motor and Body Composition Variables by Parkinson’s Disease Staging
Objective: Knowing the motor variables involved in the relationship of body composition and staging of disease. Background: Functional limitation, defined as a restriction in the…Neuroprotective propensity of PTUPB, a dual inhibitor of sEH and COX-2 against rotenone induced neurotoxicity in cell line and Drosophila model of Parkinson disease
Objective: To evaluate the potential anti-parkinson activity of PTUPB (4-(5-phenyl-3-{3-[3-(4-trifluoromethyl-phenyl)-ureido]-propyl}-pyrazol-1-yl)-benzenesulfonamide) a dual inhibitor of soluble Epoxide hydrolase (sEH) and cyclooxygenase-2 (COX-2) against rotenone induced mitochondrial dysfunction,…Nilotinib differentially affects oligomeric α-synuclein and reduces phosphorylated neurofilaments and motor symptoms in Parkinson’s disease with dementia and Lewy body dementia
Objective: This is a retrospective biomarker study of an open-label clinical study to examine the safety and efficacy of lower doses (<50% of CML dose)…Deep Learning in Objective Classification of Spontaneous Movement of Patients with Parkinson’s Disease Using Large-Scale Free-Living Sensor Data
Objective: Our goal was to classify spontaneous movement using a commercially available motion sensor in a clinically meaningful 3-/9-step discrete scale (SMS-3/SMS-9). Background: Brady-hypokinetic and dyskinetic…Tandem Standing
Objective: The aim of this study is to learn, patients who can’t make tandem standing fall more or not? Background: Falls occur more often with…A Preliminary Study: Validity and Reliability of Parkinson Fatigue Scale (PFS) in Turkish Patients with Parkinson’s Disease (PD)
Objective: The purpose of this study was to investigate the validity and reliability of the Turkish version of PFS. Background: The PFS is a 16-item…Functional Connectivity Differences Across Parkinson Disease Subtypes
Objective: The goals of this project were to 1) identify putative Parkinson disease (PD) clinical subtypes and 2) investigate resting-state functional connectivity differences between these…
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