Day case initiation of subcutaneous apomorphine in people with Parkinson’s disease: A retrospective analysis from a UK teaching hospital
Objective: To evaluate a cohort of people with Parkinson's disease (PD) who were initiated on subcutaneous apomorphine injections or continuous subcutaneous apomorphine infusions (CSAI) on…Histology of subcutaneous nodules in PD patients treated with continuous apomorphine infusion: Case series and review of the literature
Objective: To examine the histology of subcutaneous nodules after continuous subcutaneous apomorphine infusion (CSAI). Background: CSAI has been used successfully in advanced Parkinson's disease (PD).…Exercise-induced adaptive neuroplasticity in the MPTP mouse model of Parkinson’s disease
Objective: To increase our understanding of how physical exercise may drive adaptive neuroplasticity in a mouse model of Parkinson's disease (PD). Background: PD is a…The Parkinson progression marker initiative (PPMI) – Developing a comprehensive longitudinal biomarker dataset
Objective: The goal of the Parkinson Progression Marker Initiative (PPMI) is to identify clinical, imaging and biospecimen biomarkers of PD progression to provide tools for…The systemic synuclein sampling study (S4)
Objective: The Systemic Synuclein Sampling Study (S4) is designed to characterize the distribution of alpha-synuclein (α-syn) pathology in multiple tissues and biofluids in Parkinson's disease…Can intraoperative clinical testing really predict the effects of deep brain stimulation in the subthalamic nucleus?
Objective: To evaluate whether stimulation-induced therapeutic and side effects of the permanent electrode are predictable by intraoperative test stimulation with clinical examination. Background: Intraoperative test…Electric stimulation of the nucleus subthalamicus is able to modulate prepulse inhibition. A pilot study in Parkinson´s disease
Objective: To evaluate if prepulse inhibition (PPI) is influenced by electrical stimulation in the Nucleus subthalamicus (STN) of patients with Parkinson´s disease (PD). Background: PPI…Speech 10 years post bilateral STN-DBS for Parkinson’s disease
Objective: This study reports on the type and severity of speech problems up to 10 years after bilateral deep brain stimulation (DBS) of the subthalamic…DBS of the STN in 44 patients with Parkinson’s disease – Radiological and clinical outcome
Objective: Precision in implantation of deep brain stimulation (DBS) electrodes relies on systematic interdisciplinary planning and intra-operative testing and needs to be discussed along with…Apraxia of speech as the initial manifestation of progressive supranuclear palsy
Objective: We report a patient with apraxia of speech as the initial symptom who finally developed a progressive supranuclear palsy. Background: Progressive supranuclear palsy (PSP)…
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