- Impaired cerebellum to motor cortex associative plasticity in Parkinson’s diseaseObjective: To compare the corticocortical paired associative stimulation (PAS)-induced spike-timing dependent plasticity (STDP)-like plasticity between Parkinson's disease (PD) and healthy elder subjects. Background: Patients with…
- Brain mechanisms underlying visual processing in Parkinson’s diseaseObjective: We used fMRI and a visual cognitive task to study brain mechanisms underlying visual processing at different cognitive loads in patients with PD and…
- What predicts Parkinson’s disease? Hyposmia, MIBG SPECT, DAT SPECT and the PD-specific metabolic patternObjective: To compare dopaminergic imaging, cardiac sympathetic denervation, olfactory function and expression of a PD-specific metabolic cerebral pattern in patients with idiopathic REM sleep behavior…
- Cortical excitability in patients with Parkinson’s disease on levodopa carbidopa intestinal gel thereapyObjective: To assess whether there are changes in short interval intracortical inhibition (SICI) that reflect changes in motor function and plasma levodopa levels in patients…
- Optic nerve integration as a visuospatial cognitive predictor in Parkinson’s diseaseObjective: To explore the microstructural integrity of the optic nerve and its role as a cognitive predictor in patients with de novo Parkinson's disease (PD)…
- Transcranial sonography and cognitive dysfunction in Parkinson’s diseaseObjective: To evaluate the role of transcranial sonography (TCS) in discriminating between Parkinson's disease (PD) patients with normal cognition (PDNC), mild cognitive impairment (PD-MCI) and…
- Bradykinesia, low monthly income and current employment are associated with depression in patients with Parkinson’s disease: Results of a study from Sri LankaObjective: The objectives of this cross sectinal studies was to a) estimate the prevalence of depression and b) identify the associations for depression in a…
- Factors related to psychotic symptoms in patients with Parkinson’s diseaseObjective: The aim of this study was to compare clinical characteristics in Parkinson's disease (PD) with psychosis (PDP) versus PD without psychosis (PDnP) and evaluate…
- Blinded video assessment of subtle Parkinsonian signs in PREDICT-PD participantsObjective: To determine whether risk estimates calculated in PREDICT-PD are associated with objective motor features on clinical examination. Background: PREDICT-PD aims to identify a group…
- The International Parkinson and Movement Disorder Society – non-motor rating scale (MDS-NMS): Results from the cognitive pre-testing and phases 1 and 2 of an international validationObjective: To revise the Non-Motor Sumptom Scale (NMSS) and develop a new up to date version, the MDS-NMS, a project commissioned by the International Parkinson…
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