Deep brain stimulation in the STN of a Parkinsonian rat model overexpressing human A53T α-synuclein in the substantia nigra – A proof of principle
Objective: To determine if subthalamic nucleus (STN)-deep brain stimulation (DBS) leads to a measurable functional improvement of motor deficits in an AAV1/2 A53T α-synuclein (aSyn)…Is awake intraoperative mapping still necessary for bilateral subthalamic stimulation for Parkinson’s disease in a modern surgical environment?
Objective: To study the impact of the absence of awake clinical evaluation during subthalamic nucleus (STN) deep brain stimulation (DBS) on parameters of stimulation and…Idiopathic delayed-onset edema surrounding deep brain stimulation leads: Insights from a case series and systematic literature review
Objective: We present a multicenter case series of patients with idiopathic delayed-onset edema (IDE) surrounding the deep brain stimulation (DBS) leads, and a systematic literature…Autonomic failure and circadian rhythm of arterial blood pressure in IDIOPATHIC REM behaviour disorders and Parkinson’s disease
Objective: Aim of our study is to correlate the autonomic nervous system failure and circadian rhythm of arterial blood pressure in idiopathic REM behaviour disorders…Vitamin D in early Parkinson’s disease
Objective: To determine serum 25-hydroxy vitamin D (25OHD) concentration at diagnosis and 18 months in incident Parkinson's disease (PD) compared to controls and to investigate…Subjective report does not predict objective swallow impairment in atypical Parkinsonian syndromes
Objective: Swallow and speech disturbances are common in patients with atypical parkinsonism. The emergence of swallowing problems, or dysphagia, is associated with increased morbidity and…Composite autonomic symptom scale-31 (COMPASS-31) is useful for evaluation of autonomic dysfunction in patients with parkinsonism
Objective: To investigate the usefulness of composite autonomic symptom scale 31 (COMPASS-31) in patients with parkinsonism by comparing COMPASS-31 between PD and MSA patients, and…MicroRNA as diagnostic biomarkers in Parkinson’s disease and multiple system atrophy
Objective: In this study, we aimed to 1) perform miRNA profiling in CSF and subsequent 2) validate biomarker potential of differentially expressed miRs in (different)…Increased monosaccharide intake in patients with Parkinson’s disease
Objective: To verify the clinical observation that patients with Parkinson's disease (PD) have a higher consumption of monosaccharides. Background: Patients with PD frequently report an…Chin EMG variance and dream-enactment behavior during polysomnography in Parkinson’s disease
Objective: The aim of this study was to exam relationships between REM sleep muscle atonia (RSWA), dream-enactment behavior(DEB) and clinical characteristics in Parkinson's disease (PD)…
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