Cervical dystonia preceding Parkinson´s disease – Continuum – coincidence or epiphenomenon–Report of 3 cases
Objective: To report 3 cases with cervical dystonia and dystonic hand tremor who developed Parkinson´s disease (PD) years to decades later and to discuss if…Predictive validity of statistical models of Parkinson’s disease progression
Objective: To develop statistical models of Parkinson's disease (PD) progression based on a transversal assessment and to explore its predictive value in a three-year follow-up.…Inhibition of cathepsin D enhances the autophagy lysosome pathway dysfunction and α-synuclein aggregation in experimental parkinsonism
Objective: To explore the mechanism of CTSD inhibition in the dysfunction of autophagy-lysosome pathway and aggregation of α-synuclein in Parkinson's disease. Background: α-synuclein, the main…Eight weeks of home-based balance training not as effective as therapist-based during dual tasks
Objective: To assess the effect of balance training on dual-tasking gait, and to investigate if a home-based programme is comparable to a therapist-supervised programme. Background:…The CNS moving voice program: Implementation of a dual voice and physical exercise program for Parkinson’s disease: An applicability study
Objective: To test the applicability of a rehabilitation program for people with Parkinson´s disease that combines speech and motor exercises (The CNS Moving Voice Program).…Best supportive care or palliative care for late stage Parkinsonian syndromes?
Objective: To ask whether best supportive care might be more suitable for patients with Parkinson's disease (PD) and Parkinsonian syndromes and their family than palliative…Long-term safety of levodopa-carbidopa intestinal gel from an ongoing, open-label, phase 3 continued access to treatment study in advanced Parkinson’s disease patients
Objective: To assess the safety and tolerability of levodopa-carbidopa intestinal gel (LCIG, designated in the United States as carbidopa-levodopa enteral suspension) in advanced Parkinson's disease…Body position during sleep in patients with Parkinson’s disease (PD): A sensor-based analysis
Objective: To identify the body position during sleep in PD patients in comparison to their spouses by using multisite wearable inertial sensors. Background: Nocturnal hypokinesia…STEADY-PD III. A phase 3 study of isradipine as a disease modifying agent in patients with early Parkinson’s disease. Baseline characteristics of the enrolled cohort
Objective: To evaluate the efficacy of isradipine 10 mg daily on PD disability. Background: Isradipine, a dihydropyridine calcium channel antagonist with excellent penetration of the…Deep brain stimulation effect on the quality of life of individuals with Parkinson’s disease
Objective: To identify the perception of QOL in individuals with PD pre and post DBS. Background: The DBS is one type of effective treatment in…
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