The correlation between dietary fiber, fluid intake and constipation in patients with Parkinson’s disease
Objective: To clarify the correlation between high dietary fiber, fluid intake and constipation in Parkinson's disease (PD) patients. Background: Constipation is one of the complications…Levodopa-carbidopa intestinal gel via PEG-J for advanced Parkinson’s disease- A single centre experience
Objective: To investigate clinical outcome and possible complications of LCIG in patients with advanced PD in years 2006-2014 at Helsinki University Hospital. Background: Continuous levodopa-carbidopa…STN-DBS in Parkinson’s disease with early motor complications – A 10 year follow-up
Objective: To investigate long-term outcome of subthalamic stimulation (STN-DBS).in Parkinson's disease (PD) patients with early motor complications. Background: STN-DBS improves motor complications and quality of…ND0701: A novel safe concentrated apomorphine formulation for continuous subcutaneous administration via a patch pump
Objective: To characterize the local safety and PK of a novel apomorphine formulation, ND0701, in comparison to a commercially available apomorphine–HCl solution. Background: Apomorphine is…Conversion of patients from immediate release carbidopa-levodopa (IR CD-LD) and sustained release carbidopa-levodopa (SR CD-LD) to extended-release carbidopa-levodopa (ER CD-LD) in clinical practice
Objective: To evaluate the real-world response of patients who are converted from IR CD-LD and SR CD-LD to ER CD-LD in an academic practice. Background:…Taking specialist clinics into community nursing homes
Objective: Evaluate the effectiveness of delivering specialist Parkinson's care in community care home settings. Background: Our drive to improve older people's care has led to…Combined stimulation of STN and SNr for resistant freezing of gait in Parkinson’s disease (STN+SNr) – A multicenter randomized controlled trial
Objective: 54 patients with idiopathic Parkinson's disease and freezing of gait resistant to subthalamic nucleus stimulation and dopaminergic medication will be included into this German-wide…DBS targeting: Validation of 3T MR image guided targeting using post-mortem 17T MR microscopy
Objective: This work helps validate the utility of direct targeting using 3T T1 inverted sequences with atlas application during planning for DBS electrode placement. We…Role of contact polarity on therapeutic impedances at two deep brain stimulation (DBS) targets
Objective: To demonstrate the role of contact polarity on therapeutic impedances at two DBS targets. Background: Neuromodulation with DBS is an established therapy for medically…A prospective study of patients’ expectations in subthalamic nucleus deep brain stimulation for Parkinson’s disease
Objective: To prospectively assess the long-term outcome of subthalamic nucleus (STN) deep brain stimulation (DBS) and the relationship with patients' expectations and satisfaction. Background: Subthalamic…
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