RE-024: A potential phosphopantothenate replacement therapy in 2 patients with pantothenate kinase-associated neurodegeneration (PKAN)
Objective: To evaluate the safety and potential efficacy of RE-024 in open treatment of 2 patients with PKAN. Background: PKAN is an autosomal recessive, neurodegenerative…Two years after unilateral Forel’s H campotomy for Parkinson’s disease: Quality of life, motor and cognitive outcomes of eleven patients
Objective: To provide a thorough assessment of the effects of unilateral Forel's H campotomy on Parkinson's disease patients. Background: Since its proposal in 1963, Forel's…Strengths and weaknesses of patient-reported outcomes following DBS surgery: Comparing clinician, patient, and caregiver assessments
Objective: Assess the degree of correlation between DBS outcome measures rated by patients, caregivers, and clinicians. Methods: The Clinician Global Impression (CGI) score and two…MR-guided high intensity focused ultrasound in Parkinson’s disease: A series of 5 cases
Objective: We present results of an ongoing trial of unilateral transcranial MR-guided high intensity focused ultrasound (tcMRgFUS) ablation of the pallido-thalamic tract (PTT, fasciculus thalamicus)…Cognitive outcome in the patients with Parkinson’s disease one year after subthalamic implants in Taiwan
Objective: To demonstrate cognitive outcome after subthalamic deep brain stimulation(DBS) in the patients with Parkinson's disease(PD) in Taiwan. Background: Deep brain stimulation of the subthalamic…Bacterial biofilm formation on neurostimulation systems
Objective: The aim of this study is to identify specifically the DNA of bacterial biofilm on neurostimulation systems using polymerase chain reaction (PCR). Background: Bacterial…Influence of onset age on the progression of non-motor symptoms in Parkinson’s disease: A prospective study from Southwest China
Objective: To explore the influence of onset age on the progression of non-motor symptoms (NMS) in Parkinson's disease. Background: NMS are gaining increasing relevance in…Microglia P2Y6 receptor is related to Parkinson’s disease and involved in the neuroinflammatory process
Objective: To investigate whether the purinoceptor P2Y6 can be used as a biomarker in the diagnosis and treatment of Parkinson's disease (PD) and the role…EBM review on the diagnostic work-up of multiple system atrophy
Objective: The International Parkinson and Movement Disorder Society (MDS)-endorsed MSA study group (MODIMSA) identified an urgent need to develop evidence-based recommendations for the diagnostic work-up…Cognitive functioning in Parkinson’s disease and Parkinson plus syndrome
Objective: Our study aimed to investigate and compare the cognitive functioning in PD and PPS. Background: Parkinson[s] disease (PD) is now known to be associated…
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