Traditional trial-and-error versus neuroanatomical-3D-image software-assisted deep brain stimulation programming in patients with Parkinson’s disease
Objective: To compare traditional trial-and-error with neuroanatomical-3D-image software-assisted deep brain stimulation (DBS) programming in patients with Parkinson's disease (PD) treated with subthalamic nucleus (STN) DBS.…Reduction in battery longevity for each subsequent implantable pulse generator (IPG) in patients with Parkinson’s disease (PD) treated with bilateral subthalamic nucleus deep brain stimulation (STN-DBS) may be due to both programming changes and IPG model – a case series
Objective: To determine whether the decrease in longevity following IPG replacement is due to programming changes and whether there is an effect of IPG model.…Atypical parkinsonism in C9orf72 expansions: A case report and systematic review of 45 cases from the literature
Objective: To provide a systematic clinical characterisation of C9orf72-associated parkinsonism. Background: While C9orf72 repeat expansions usually present with frontotemporal dementia (FTD) and/or amyotrophic lateral sclerosis…Serum levels of polychlorinated biphenyls, CYP2B6 and neurodegenerative disease in the Faroe Islands
Objective: To investigate genetic variability in CYP2B6, PCB levels and Parkinson's disease in the Faroese. Background: Polychlorinated biphenyls (PCBs) are persistent man-made highly toxic pollutants…Auditory function and speech discrimination abilities are impaired in progressive supranuclear palsy
Objective: To find out hearing ability and speech discrimination of progressive supranuclear palsy (PSP) patients, we performed audiological evaluation by means of Pure Tone (PTA)…Generation and characterization of iPSC-derived nigral dopaminergic and pyramidal glutamatergic neurons from patients affected by multiple system atrophy
Objective: The aim of the present study is to generate dopaminergic and pyramidal neurons from iPSCs of MSA patients in order to establish an in…Can deep brain stimulation implantation cause multiple system atrophy? A retrospective review of MSA patients
Objective: To evaluate whether implantation of deep brain stimulation (DBS) could lead to multiple system atrophy (MSA). Background: Recent studies regarding the transmissibility of alpha-synuclein…Non-motor symptoms trajectory in Parkinson’s disease: Magnitude and importance of the change
Objective: To determine the magnitude and clinical relevance of the change of non-motor symptoms (NMS) in Parkinson's disease (PD) patients over a 2-year follow-up. Background:…RBD increase non-motor symptom in Parkinson’s disease
Objective: To investigate the relationship between the RBD and other non-motor symptoms in Parkinson's disase. Background: Rapid eye movement sleep behavior disorder (RBD) is frequent…Anosmia predicts development of more severe motor symptoms including freezing of gait and impaired balance at 2 year follow-up in PD
Objective: To investigate the relationship between baseline anosmia and 2-yr interval development of motor impairments in Parkinson's disease (PD). Background: More severe olfactory deficits have…
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