Characterization of striatal TH-immunoreactive cells in chronic and acute L-DOPA treatment in a mice model of Parkinson´s disease
Objective: To characterize Tyrosine Hydroxylase immunoreactive cells (TH-ir) in a mouse model of hemiparkinsonism and L-DOPA induced dyskinesia. Background: L-DOPA-induced dyskinesias (LID) are a severe…Relative hypoglycemia induces acute chorea followed by chronic parkinsonism in a diabetic patient on hemodialysis: A case with sequential clinico-radiological correlate
Objective: To present a sequential clinico-radiological study of a diabetic patient on hemodialysis who developed acute chorea followed by chronic parkinsonism. Background: Hyperglycemic chorea is…Anti-GAD antibody cerebellar ataxia mimicking multiple system atrophy
Objective: To describe a case of anti-glutamic acid decarboxylase antibody (GAD-Abs)-associated cerebellar ataxia (CA), which presented with gradual dysautonomia and parkinsonism fulfilling criteria for MSA,…The role of cathepsin L involved in the activation of microglia and Parkinson’s disease
Objective: To investigate the role of lysosomal protease cathepsin L in the activation of microglia and the injury of dopaminergic neurons, and further to interpret…Correlation between Parkinson’s disease and malignant tumors
Objective: We have carried out the research among the group of Sardinian patients with PD, led by our Ambulatory of Movement Disorders, to evaluate the…Visual vs. automated analysis of [123I]FP-CIT SPECT scans in patients with parkinsonism
Objective: To investigate the differences between visual and automated analyses of brain dopamine transporter (DAT) SPECT scans. Background: Clinical evaluation of DAT SPECT scans typically…Inferring the coupling of motor related brain areas during paced finger tapping in Parkinson’s patients
Objective: To analyze the coupling and causal interplay of motor related brain areas in Parkinson's patients during the performance of externally and internally paced finger…Negative emotional signals impair isometric force control in Parkinson’s disease
Objective: To investigate the effect of sustained exposure to negative emotional stimuli on isometric grip-force control in Parkinson's disease (PD). Background: Recent animal studies have…Neuropsychology and magnetic resonance correlation in Parkinson´s disease mild cognitive impairment: Case-control study
Objective: Evaluate the relationship between magnetic resonance (MRI) abnormalities and neuropsychological assessment in Parkinson s disease mild cognitive impairment (PD-MCI) and controls with mild cognitive…Circulatory levels of BDNF correlate with cognitive deficits in people with Parkinson’s disease
Objective: The aim of this study was to examine the relationship of serum BDNF levels with cognitive function. Background: Brain-derived neurotrophic factor (BDNF) is essential…
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