Severe Dopaminergic Deficits in Early Stage Genetically-Confirmed Perry Syndrome
Objective: To describe the evidence for severe dopaminergic deficit in early stages of genetically confirmed Perry syndrome Background: PS is a neurodegenerative disease comprised of…Parkinsonism in KMT5B-related Disorders: Expanding the Spectrum.
Objective: To describe a novel association between parkinsonism and a pathogenic variant in the KMT5B gene, expanding the clinical spectrum of KMT5B-related disorders. Background: Neuropsychiatric…The importance of vascular anomalies and endothelin-1 factor in the development of vascular parkinsonism
Objective: To study the relationship between vascular endothelium and vascular anomalies in the development of vascular parkinsonism. Background: Although vascular parkinsonism (VP) is relatively rare,…The Sedentary Index (SI) for Daily Life Activity Monitoring in Progressive Supranuclear Palsy (PSP)
Objective: To confirm the feasibility of daily life physical activity monitoring in PSP using a single activPAL sensor, and to examine preliminary associations between overall…The IMPACT study: protocol of a randomised controlled single-blind trial evaluating efficacy and cost-effectiveness of telenursing in atypical parkinsonism
Objective: To present the protocol of a study evaluating the efficacy and cost-effectiveness of a 12-month integrated program aimed at improving healthcare delivery and coordinated…Survey of knowledge and training needs of professionals in nursing homes for Parkinson’s disease
Objective: Understand the initial knowledge of Nursing home professionals. Target the learning weaknesses. Generate spontaneous demand for training spontaneous demand for training and topics to help professionals…Chronic kidney disease, proteinuria, and mortality risk in patients with Parkinson’s disease: A longitudinal study
Objective: To investigate whether chronic kidney disease (CKD) and proteinuria are associated with mortality rates in patients with Parkinson's disease (PD), using data from a large…A Prospective, Observational Study to Identify Biomarkers in Parkinsonian Syndromes (proATYP).
Objective: This is a prospective observational study to identify biomarkers in parkinsonian syndromes. Background: Parkinson’s disease (PD) and atypical parkinsonian syndromes namely progressive supranuclear palsy…Secular trends and survival of Parkinson’s disease and other forms of parkinsonism in the United Kingdom
Objective: We examined the UK incidence, prevalence and survival for eight parkinsonian disorders including Parkinson’s disease (PD) from 2003 to 2023, using primary and secondary…Early-onset levodopa-responsive parkinsonism with cognitive impairment and head-bobbing dyskinesias associated with SYNJ1 and GBA variants of unknown significance
Objective: Describe the clinical and diagnostic findings of a patient with early-onset Parkinson’s Disease (EOPD) with homozygous variant of unknown significance (VUS) in the SYNJ1…
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