The PD-1102 trial in advanced Parkinson’s disease: safety and clinical outcomes from a 3-year phase 1b study of AADC gene therapy administered via a posterior approach
Objective: To present 3-year safety and clinical outcome data from a phase 1b, open-label trial of VY-AADC01 (NBIb-1817) for Parkinson’s disease (PD) patients with motor…A retrospective review of clinical features of Progressive Supranuclear Palsy (PSP) in a movement disorders clinic
Objective: Understanding the common clinical features of PSP. Background: PSP is a relatively rare progressive neurodegenerative disease, which can often be difficult to distinguish from…Parkinsonism in a patient with limbic-predominant age-related TDP-43 encephalopathy (LATE) syndrome
Objective: To illustrate a case of parkinsonism in a patient with LATE syndrome. Background: LATE syndrome is an emerging subclassification of TDP-43 proteinopathy. Symptoms include…CSF MicroRNA Analysis Reveals Angiogenesis And Autophagy Defects In Parkinson’s DiseasePatients
Objective: We investigated the effects of discoidin domain receptor (DDR)-1 inhibition on CSF miRNAs in Parkinson’s disease patients. Background: MicroRNAs (miRNAs) are post-transcriptional regulators of…Clinical characteristics and factors associated musculoskeletal pain in Parkinson’s disease: A retrospective study from two centers in China
Objective: To investigate the distribution, clinical characteristics, and factors associated with MSP in a large sample of patients with PD. Background: Musculoskeletal pain (MSP) is…A physical therapy of postural reeducation with a tilt table for a patient with Parkinson’s disease complicated with dropped head syndrome
Objective: The purpose of our study is to evaluate the effect of postural reeducation with a tilt table in a Parkinson’s disease patient with dropped head…New presenilin-1 missense variant (p.Pro88Arg) characterized by initial progressive supranuclear palsy like phenotype.
Objective: To report a new presenilin-1 (PSEN 1) missense variant (p.Pro88Arg) characterized by initial Progressive Supranuclear Palsy (PSP) like phenotype. Background: Pathogenic variants in the PSEN1gene…Apomorphine Sublingual Film for “OFF” Episodes in Parkinson’s Disease: Impact on Impulse Control Disorders
Objective: Assess impact of apomorphine sublingual film (APL) on impulse control disorders (ICDs) in patients with Parkinson’s disease (PD) and “OFF” episodes. Background: In a…Classification of Advanced Parkinson’s Disease in OBSERVE-PD Patients Based on the MANAGE-PD Screening Tool
Objective: This post-hoc analysis evaluated uncontrolled patients from OBSERVE-PD identified as advanced Parkinson’s disease (APD) based on domains evaluated in section 2 of the MANAGE-PD…Backward Fall Protection Garment for patients of PSP and other Parkinsonian Syndromes.
Objective: To create a sensor controlled wearable system with an inflatable collar that offers protection against head, spine and shoulder girdle injuries in case of…
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