Safety, Target Engagement and Effects of Bosutinib in Dementia with Lewy Bodies
Objective: To investigate the safety, biomarkers effects and determine the lowest effective dose of Bosutinibin Dementia with Lewy Bodies (DLB) Background: The effects of bosutinib,…Advance Care Planning and Parkinson’s disease: patient knowledge assessment
Objective: Evaluate disease knowledge in patients with Parkinson’s disease in an Advance Care Planning (ACP) clinic. Background: Poor disease knowledge has been associated with misconceptions…Adults with slowly progressive dystonia-parkinsonism secondary to manganese accumulation
Objective: To expand the clinical spectrum of manganese-induced neurodegeneration. Background: Neurodegeneration induced by manganese accumulation is a potentially treatable condition and therefore should not be…Association of type 2 diabetes and dementia in elderly patients with Parkinson’s disease: a population-based study in Korea
Objective: This study aimed to investigate the impact of type 2 diabetes (T2DM) on the development of dementia in patients with Parkinson’s disease (PD). Background:…Perceptions of persons with Parkinson’s disease towards telemedicine as an alternative mode of consultation: An International Pre-Implementation Survey
Objective: To assess the preferences and perceptions of persons living with Parkinson’s disease (PD) towards virtual consultations as an option for out-patient consultations. Background: Global…Discrimination in Healthcare for Parkinsonism Across Sexual and Gender Minority Groups
Objective: To compare perceived discrimination in healthcare across men, women and LBGTQ+ people with parkinsonism Background: Stigma, often experienced by people with parkinsonism and care…Mimics or multiplicity: two patients with a PSP phenotype and underlying genetic neurodegenerative disorders.
Objective: To describe a two cases of patients presenting with a PSP phenotype and genetic findings consisted with Huntington’s disease (HD) in one case and…Beta-agonists and risk of Parkinson’s disease: Meta-analysis of real-world evidence studies
Objective: We performed a systematic review and meta-analysis of real-world evidence (RWE) studies evaluating the association between use of beta-agonist and the risk of PD.…Impulse Control Disorders Following Bilateral Subthalamic Deep Brain Stimulation for Parkinson’s Disease: The INTREPID Randomized Controlled Trial
Objective: To assess the frequency and outcomes of impulsivity in study participants receiving bilateral subthalamic deep brain stimulation (STN-DBS) for the treatment of Parkinson’s Disease…Synaptic density in cortical and subcortical gray matter is associated with mild parkinsonian signs (MPS) in healthy older adults: a [11C] UCB-J PET study
Objective: to investigate if a reduction in cortical and subcortical synaptic density measured in vivo with the synaptic vesicle protein 2A (SV2A) binding [11C] UCB-J…
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