Effect of the mGlu2/3 orthosteric agonist LY-404,039 on abnormal involuntary movements and parkinsonism in the 6-OHDA-lesioned rat
Objective: To assess the effect of LY-404,039 on dyskinesia and parkinsonism in the 6-hydroxydopamine (6-OHDA)-lesioned rat model of Parkinson’s disease (PD). Background: LY-404,039 is an…Idiopathic rhombencephalitis involving the substantia nigra followed by rapidly progressive parkinsonian syndrome in a young patient
Objective: To describe a unique case of a healthy 21-year-old female patient diagnosed with idiopathic rhombencephalitis with predominant parkinsonian clinical signs who later developed severe…Baseline cognitive profile is closely associated with long-term motor prognosis in newly diagnosed Parkinson’s disease
Objective: To investigate the association between cognitive function at baseline and the progression of motor disability in Parkinson’s disease (PD). Background: There is increasing clinical…Movement-related dynamics of β-γ phase-amplitude coupling in repetitive movement tasks of Parkinson disease
Objective: In this study, we aim to understand the functional role of β-γ phase amplitude coupling (PAC) during repetitive movement tasks and its relationship with…Visual Impairment along Parkinsonism Development and the Association to Non-vision dependent Cognitive Decline: A Prospective Nation-wide CLSA study
Objective: To assess the associations of ocular physiology and visual function with the development of parkinsonism in a prospective population-based study. Background: Several clinical studies…Safety and effectiveness of unilateral MRgFUS thalamotomy in elderly patients with essential and parkinsonian tremor
Objective: This study aims at assessing safety and effectiveness of Magnetic Resonance-guided Focused High Intensity Ultrasound (MRgFUs) thalamotomy in elderly patients with essential and parkinsonian…Brain SPECT in Patients with Akinetic-Rigid Syndrome Secondary to Radiotherapy
Objective: The aim of this study is to evaluate the results of brain single photon emission computed tomography (SPECT) with 123-iodine ioflupane in patients with brain…Apomorphine Sublingual Film for “OFF” Episodes in Parkinson’s Disease: Analysis of Baseline Factors
Objective: Determine if baseline factors are associated with the apomorphine sublingual film (APL) dose required to achieve FULL “ON.” Background: APL is approved for the…Neuroprotective Epigenetic and DNA-Repair Molecular Mechanisms of Acetyl-L-Carnitine and Astaxanthin Against 6-OHDA Induced Parkinsonism in Aged Rats
Objective: Present study was designed to delineate the neuroprotective epigenetic and DNA-damage-repair molecular mechanisms of acetyl-L-carnitine (ALC) and astaxanthin (ASX) against 6-OHDA-induced neurotoxicity in aged…A Rare Case of Reversible Acute Parkinsonism in Fulminant HIV Encephalopathy
Objective: - Background: HIV infection of the central nervous system can be a result of direct neuroinflammatory processes or by opportunistic infections. Movement disorders in…
- « Previous Page
- 1
- …
- 55
- 56
- 57
- 58
- 59
- …
- 388
- Next Page »