Cellular Modeling of Tyrosine Hydroxylase Deficiency Recapitulates Patient Phenotypes and Response to Treatment.
Objective: Characterize a new cellular model of Tyrosine Hydroxylase deficiency (THD) based on induced pluripotent stem cells (iPSCs) to better understand the pathophysiology and test…Novel quantitative measures with standardised graphical tasks to objectively assess subtle changes in fine motor skill in diagnosing and monitoring of Parkinson’s disease
Objective: To integrate a handheld device with standardised graphical tasks into clinical assessment for automated objective motor symptoms rating with digital record keeping in Parkinson’s…Racial and ethnic differences in patients with Parkinson’s Disease across Parkinson’s Disease Centers of Excellence
Objective: To investigate treatment, health-related quality of life, and other outcome differences in patients with Parkinson’s Disease (PD) across race and ethnicity. Background: The inclusion…Terminal Choking in Parkinson’s Disease
Objective: To establish whether choking is a frequent cause of death in Parkinson’s Disease (PD), if this is a feared consequence of PD in patients/caregivers…Long-Term Evaluation of Deep Brain Stimulation for Treatment of Parkinson’s Disease Using a Multiple-Source, Constant-Current Rechargeable System: 4-year Follow-Up of a Prospective, Double-Blind RCT
Objective: The long-term effectiveness of a Deep Brain Stimulation (DBS) device capable of Multiple Independent Current Control (MICC) is assessed in a prospective, sham-controlled, double-blind…Benign Progressive Supranuclear Palsy: mild pathology associated with parkinsonism
Objective: Objective: To describe the clinical presentation and neuropathology of cases where the degree of tau pathology is mild, and the neuronal loss is anatomically…ELECTRICAL ACTIVITY OF THE MASTICATORY MUSCLES OF PARKINSONIANS INFLUENCED BY THE USE OF REMOVABLE DENTAL PROSTHESIS
Objective: Analyze the influence of the types of dental prosthesis on the electromyographic activity of the masticatory muscles; masseter and temporal anterior in parkinsonians. Background:…Remote assessment of prodromal Parkinson’s disease in a LRRK2 G2019S cohort
Objective: To compare remote application of the Movement Disorder Society (MDS) prodromal Parkinson’s disease (PD) criteria to expert clinical determination of possible parkinsonism in a…PARKINSON’S DISEASE AND COVID-19 PANDEMIC: MODIFICATIONS IN MOTOR AND NON-MOTOR SYMPTOMS AND IN THE ACCESS TO MEDICAL AND NON-MEDICAL CONSULTATIONS AND TREATMENTS
Objective: The objective was to determine in a group of PD patients their perception of how isolation measures during the pandemic affected their motor and…The complexity metric of hand tremor identifies Parkinsonian tremor and essential tremor
Objective: To examine the specificity and sensitivity of complexity metric derived from hand tremor fluctuation in the identification of Parkinsonian tremor (PT) from essential tremor…
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