Spatiotemporal Changes in Substantia Nigra Neuromelanin Content from Prodromal to Clinical Parkinson’s Disease
Objective: To investigate the voxel-wise spatiotemporal changes in neuromelanin-sensitive MRI (NM-MRI) signal in the substantia nigra and their relation to clinical scores of disease severity…Disrupted functional brain connectome at the early non-freezing stage of Parkinson’s disease patients with freezing of gait
Objective: To investigate topological organization of the functional brain connectome at the early non-freezing stage of Parkinson’s disease (PD) patients with freezing of gait (FOG).…Automated pattern based classification in neuropathology proven parkinsonism
Objective: In patients with parkinsonism and uncertain differential diagnosis, an automated image-based algorithm can help to distinguish idiopathic Parkinson’s disease (IPD) from atypical parkinsonian syndromes…A reliable measure of rigidity with a novel robotic device
Objective: The objective of our study was to objectively measure the rigidity in PD patients, using a recently validated robotic device. Background: Rigidity is one…Excessive Daytime Sleepiness in Parkinson’s disease and Narcolepsy Genetic Risk Allele HLA DQB1*0602
Objective: To determine whether narcolepsy risk allele HLA DQB1*0602 is associated with excessive daytime sleepiness (EDS) in patients with Parkinson's disease (PD) on dopaminergic agents.…The Clinical Heterogeneity of Orthostatic Hypotension in PD Patients
Objective: The objects of the research were to investigate the clinical heterogeneity of orthostatic hypotension(OH) in PD Patients, to explore the possible risk factors for…Dietary insights of Parkinson’s Disease patients
Objective: To report on the patterns of nutritional intake in an Australian Parkinson’s disease (PD) cohort. Background: There is limited information about the dietary habits…Insomnia may have a mediating role in linking Parkinson’s disease severity to depression and anxiety
Objective: The aim of this study was to investigate the role of insomnia in relationship of disease severity with depression/anxiety in patients with Parkinson’s disease…Prevalence, Impact, and Suboptimal Treatment of Depression in the Fox Insight Cohort
Objective: Addressing unmet mental health needs in Parkinson’s disease (PD) requires delineating their scope and impact. This study evaluated (1) depressive symptom prevalence and treatment…Using mindfulness to improve self-awareness in Parkinson’s disease patients – preliminary results of a randomized controlled trial
Objective: This clinical trial aims to investigate the effects and feasibility of a newly developed 8-week mindfulness intervention on self-awareness in Parkinson’s disease (PD) patients.…
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